7 Result(s)

Article

Menstrual blood-derived mesenchymal stem cells combined with collagen I gel as a regenerative therapeutic strategy for degenerated disc after discectomy in rats

Annulus fibrosis (AF) defects have been identified as the primary cause of disc herniation relapse and subsequent disc degeneration following discectomy. Stem cell-based tissue engineering offers a promising a...

Li Yu, Honghao Wu, Shumei Zeng, **aojian Hu, Yuxu Wu… in Stem Cell Research & Therapy (2024)

Article

Comparative proteomic profiling of plasma exosomes in lung cancer cases of liver and brain metastasis

Metastases within liver or the brain are the most common causes of mortality from lung cancer (LC). Predicting liver or brain metastases before having evidence from imaging of the tumors is challenging but imp...

Sini Li, Yan Qu, Lihui Liu, Xue Zhang, Yan He, Chao Wang, Yufeng Guo… in Cell & Bioscience (2023)

Article

Human menstrual blood-derived stem cells reverse sorafenib resistance in hepatocellular carcinoma cells through the hyperactivation of mitophagy

Sorafenib is a first-line drug targeting the RTK-MAPK signalling pathway used to treat advanced hepatocellular carcinoma (HCC). However, tumour cells readily develop sorafenib resistance, limiting long-term th...

Sining Zhou, Yiming Liu, Qi Zhang, Huikang Xu, Yangxin Fang… in Stem Cell Research & Therapy (2023)

Article

Legacy of Hongxi Su: Pioneer of Chinese Cardiosurgery

Sumin Yang, Haoyu Hu, **n Zheng, Shizhong Wang, Li Yuan in Protein & Cell (2022)

Article

EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma

Epstein–Barr virus (EBV) was the first oncogenic virus identified in humans. It is primarily associated with multiple lymphoid and epithelial cancers, including nasopharyngeal carcinoma (NPC). However, its ass...

Li Yuan, Shibing Li, Qiuyan Chen, Tianliang **a… in Cell Death & Differentiation (2022)

Article

SIRT1 attenuates renal fibrosis by repressing HIF-2α

Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD⁺)-dependent deacetylase belonging to class III histone deacetylases. Previous studies have shown that SIRT1 is involved in kidney physiology regulatio...

Peipei Li, Yue Liu, **aogang Qin, Kairen Chen, Ruiting Wang… in Cell Death Discovery (2021)

Article

Human menstrual blood-derived stem cells mitigate bleomycin-induced pulmonary fibrosis through anti-apoptosis and anti-inflammatory effects

Idiopathic pulmonary fibrosis is a kind of diffuse interstitial lung disease, the pathogenesis of which is unclear, and there is currently a lack of good treatment to improve the survival rate. Human menstrual...

**n Chen, Yi Wu, Yanling Wang, Lijun Chen, Wendi Zheng… in Stem Cell Research & Therapy (2020)