38 Result(s)

Article

Menstrual blood-derived mesenchymal stem cells combined with collagen I gel as a regenerative therapeutic strategy for degenerated disc after discectomy in rats

Annulus fibrosis (AF) defects have been identified as the primary cause of disc herniation relapse and subsequent disc degeneration following discectomy. Stem cell-based tissue engineering offers a promising a...

Li Yu, Honghao Wu, Shumei Zeng, **aojian Hu, Yuxu Wu… in Stem Cell Research & Therapy (2024)

Article

CircMAST1 inhibits cervical cancer progression by hindering the N4-acetylcytidine modification of YAP mRNA

Cervical cancer (CCa) is the fourth most common cancer among females, with high incidence and mortality rates. Circular RNAs (circRNAs) are key regulators of various biological processes in cancer. However, th...

Chunyu Zhang, Li Yuan, Qiaojian Zou, Caixia Shao… in Cellular & Molecular Biology Letters (2024)

Article

The novel developed microsatellite markers revealed potential hybridization among Cymbidium species and the interspecies sub-division of C. goeringii and C. ensifolium

Orchids (Cymbidium spp.) exhibit significant variations in floral morphology, pollinator relations, and ecological habitats. Due to their exceptional economic and ornamental value, Cymbidium spp. have been commer...

Hui-Juan Ning, Fang-Fang Gui, En-Wei Tian, Li-Yuan Yang in BMC Plant Biology (2023)

Article

Comparative proteomic profiling of plasma exosomes in lung cancer cases of liver and brain metastasis

Metastases within liver or the brain are the most common causes of mortality from lung cancer (LC). Predicting liver or brain metastases before having evidence from imaging of the tumors is challenging but imp...

Sini Li, Yan Qu, Lihui Liu, Xue Zhang, Yan He, Chao Wang, Yufeng Guo… in Cell & Bioscience (2023)

Article

Inhibition of ERK downregulates autophagy via mitigating mitochondrial fragmentation to protect SH-SY5Y cells from OGD/R injury

Cerebral ischemia-reperfusion injury (CIRI) is the main cause leading to high mortality and neurological disability in patients with cardiac arrest/cardiopulmonary resuscitation (CA/CPR). Our previous study fo...

Zhang-Li Yuan, Yan-Zi Mo, De-Li Li, Lu **e… in Cell Communication and Signaling (2023)

Article

Retraction Note: Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/ NQO1 axis via downregulating miR-450b-5p

Wei Huang, Guangqing Shi, Zhong Yong, Jian Li, Juan Qiu, Yan Cao… in Cell Death & Disease (2023)

Article

Human menstrual blood-derived stem cells reverse sorafenib resistance in hepatocellular carcinoma cells through the hyperactivation of mitophagy

Sorafenib is a first-line drug targeting the RTK-MAPK signalling pathway used to treat advanced hepatocellular carcinoma (HCC). However, tumour cells readily develop sorafenib resistance, limiting long-term th...

Sining Zhou, Yiming Liu, Qi Zhang, Huikang Xu, Yangxin Fang… in Stem Cell Research & Therapy (2023)

Article

Legacy of Hongxi Su: Pioneer of Chinese Cardiosurgery

Sumin Yang, Haoyu Hu, **n Zheng, Shizhong Wang, Li Yuan in Protein & Cell (2022)

Article

EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma

Epstein–Barr virus (EBV) was the first oncogenic virus identified in humans. It is primarily associated with multiple lymphoid and epithelial cancers, including nasopharyngeal carcinoma (NPC). However, its ass...

Li Yuan, Shibing Li, Qiuyan Chen, Tianliang **a… in Cell Death & Differentiation (2022)

Article

Genetic testing enables a precision medicine approach for nephrolithiasis and nephrocalcinosis in pediatrics: a single-center cohort

Hereditary factors are the main cause of pediatric nephrolithiasis (NL)/nephrocalcinosis (NC). We summarized the genotype–phenotype correlation of hereditary NL/NC in our center, to evaluate the role of geneti...

Lin Huang, Chang Qi, Gaohong Zhu, Juanjuan Ding, Li Yuan… in Molecular Genetics and Genomics (2022)

Article

The circadian clock ticks in plant stress responses

The circadian clock, a time-kee** mechanism, drives nearly 24-h self-sustaining rhythms at the physiological, cellular, and molecular levels, kee** them synchronized with the cyclic changes of environmenta...

**aodong Xu, Li Yuan, Qiguang **e in Stress Biology (2022)

Article

The thiol-disulfide exchange activity of AtPDI1 is involved in the response to abiotic stresses

Arabidopsis protein disulfide isomerase 1 (AtPDI1) has been demonstrated to have disulfide isomerase activity and to be involved in the stress response. However, whether the anti-stress function is directly rela...

Ying Lu, Li Yuan, Zhou Zhou, Mengyu Wang, **aoyun Wang, Shizhong Zhang… in BMC Plant Biology (2021)

Article

Circular RNA hsa_circ_0043280 inhibits cervical cancer tumor growth and metastasis via miR-203a-3p/PAQR3 axis

Circular RNAs (circRNAs) are known to act as key regulators in a variety of malignancies. However, the role of circRNAs in cervical cancer (CCa) remains largely unknown. Herein, we demonstrated that a circRNA ...

Chunyu Zhang, Pan Liu, Jiaming Huang, Yuandong Liao, Chaoyun Pan… in Cell Death & Disease (2021)

Article

Genome wide analysis of kinesin gene family in Citrullus lanatus reveals an essential role in early fruit development

Kinesin (KIN) as a motor protein is a versatile nano-machine and involved in diverse essential processes in plant growth and development. However, the kinesin gene family has not been identified in watermelon,...

Shujuan Tian, Jiao Jiang, Guo-qi Xu, Tan Wang, Qiyan Liu, **ner Chen… in BMC Plant Biology (2021)

Article

Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

Targeted sequencing using oncopanels requires comprehensive assessments of accuracy and detection sensitivity to ensure analytical validity. By employing reference materials characterized by the U.S. Food and ...

Binsheng Gong, Dan Li, Rebecca Kusko, Natalia Novoradovskaya, Yifan Zhang… in Genome Biology (2021)

Article

SIRT1 attenuates renal fibrosis by repressing HIF-2α

Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD⁺)-dependent deacetylase belonging to class III histone deacetylases. Previous studies have shown that SIRT1 is involved in kidney physiology regulatio...

Peipei Li, Yue Liu, **aogang Qin, Kairen Chen, Ruiting Wang… in Cell Death Discovery (2021)

Article

Human menstrual blood-derived stem cells mitigate bleomycin-induced pulmonary fibrosis through anti-apoptosis and anti-inflammatory effects

Idiopathic pulmonary fibrosis is a kind of diffuse interstitial lung disease, the pathogenesis of which is unclear, and there is currently a lack of good treatment to improve the survival rate. Human menstrual...

**n Chen, Yi Wu, Yanling Wang, Lijun Chen, Wendi Zheng… in Stem Cell Research & Therapy (2020)

Article

Mandarin fish (Sinipercidae) genomes provide insights into innate predatory feeding

Mandarin fishes (Sinipercidae) are piscivores that feed solely on live fry. Unlike higher vertebrates, teleosts exhibit feeding behavior driven mainly by genetic responses, with no modification by learning fro...

Shan He, Ling Li, Li-Yuan Lv, Wen-**g Cai, Ya-Qi Dou, Jiao Li… in Communications Biology (2020)

Article

RETRACTED ARTICLE: Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/NQO1 axis via downregulating miR-450b-5p

Dysregulation of RKIP and NRF2 has been widely involved in the therapy resistance of multiple malignances, however, their relation and the corresponding mechanisms, especially in radiation response, have not b...

Wei Huang, Guangqing Shi, Zhong Yong, Jian Li, Juan Qiu, Yan Cao… in Cell Death & Disease (2020)

Article

Dynamics of fungal communities during Gastrodia elata growth

Gastrodia elata is a widely distributed achlorophyllous orchid and is highly valued as both medicine and food. Gastrodia elata produces dust-like seeds and relies on mycorrhizal fungi for its germination and grow...

Lin Chen, Yu-Chuan Wang, Li-Yuan Qin, Hai-Yan He, **an-Lun Yu… in BMC Microbiology (2019)