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Article
Parameter identification and pressure control of dynamic system in shield tunneling using least squares method
An estimation approach using least squares method was presented for identification of model parameters of pressure control in shield tunneling. The state equation of the pressure control system for shield tunn...
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Article
Electronic properties of the halogen bonds Z3CX···Y− between halide anions and methyl halides
In this study, the linear halogen bonds Z3CX···Y– (X = Cl, Br; Y, Z = F, Cl, Br) are theoretically investigated. They have large interaction energies—23–160 kJ/mol, and the interactions are closed-shell in nature...
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Article
Experimental study on the pressure control of soil chamber in shield tunneling
A mathematical model of the soil pressure system in shield tunneling was proposed to optimize soil pressure control in the soil chamber, based on the constitutive relationship between strain and stress. The de...
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Article
Combined effects of a high-fat diet and chronic valproic acid treatment on hepatic steatosis and hepatotoxicity in rats
To investigate the potential interactive effects of a high-fat diet (HFD) and valproic acid (VPA) on hepatic steatosis and hepatotoxicity in rats.
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Article
Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice
In the penumbra after focal cerebral ischemia, an increase of protease Omi is linked to a decrease of Hs1-associated protein X-1 (Hax-1), a protein belonging to the Bcl-2 family. In this study we investigated ...
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Article
Ginsenosides synergize with mitomycin C in combating human non-small cell lung cancer by repressing Rad51-mediated DNA repair
The use of ginseng extract as an adjuvant for cancer treatment has been reported in both animal models and clinical applications, but its molecular mechanisms have not been fully elucidated. Mitomycin C (MMC),...
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Article
Open AccessThe predictive role of CD4+ cell count and CD4/CD8 ratio in immune reconstitution outcome among HIV/AIDS patients receiving antiretroviral therapy: an eight-year observation in China
The immune reconstitution after initiation of highly active antiretroviral therapy (HAART) among HIV-infected individuals substantially affects patients’ prognosis. However, the dynamic characteristics and pre...
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Article
Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure
Programmed cell death (PCD), including apoptosis, apoptotic necrosis, and pyroptosis, is involved in various organ dysfunction syndromes. Recent studies have revealed that a substrate of caspase-3, gasdermin E...
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Article
Engineering FeOOH/Ni(OH)2 heterostructures on Ni3S2 surface to enhance seawater splitting
The construction of highly stable and efficient electrocatalysts is desirable for seawater splitting but remains challenging due to the high concentration of Cl− in seawater. Herein, FeOOH/Ni(OH)2 heterostructure...