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    Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure

    Programmed cell death (PCD), including apoptosis, apoptotic necrosis, and pyroptosis, is involved in various organ dysfunction syndromes. Recent studies have revealed that a substrate of caspase-3, gasdermin E...

    Wan-feng Xu, Quan Zhang, Chu-jie Ding, Hui-yong Sun, Yuan Che… in Acta Pharmacologica Sinica (2021)