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Article
Open AccessCorrection to: YAP1 acts as a negative regulator of pro-tumor TAZ expression in esophageal squamous cell carcinoma
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Article
Open AccessYAP1 acts as a negative regulator of pro-tumor TAZ expression in esophageal squamous cell carcinoma
Although YAP1 and TAZ are believed to be equivalent downstream effectors of the Hippo pathway, differential expression of YAP1 or TAZ suggests distinct functions during cancer progression. The exact role of YA...
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Article
Open AccessThe p53-S100A2 Positive Feedback Loop Negatively Regulates Epithelialization in Cutaneous Wound Healing
The S100A2 protein is an important regulator of keratinocyte differentiation, but its role in wound healing remains unknown. We establish epithelial-specific S100A2 transgenic (TG) mice and study its role in woun...
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Article
Open AccessCharacterization of membranous and cytoplasmic EGFR expression in human normal renal cortex and renal cell carcinoma
Metastatic renal cell carcinoma (RCC) is highly resistant to conventional systemic treatments, including chemotherapy, radiotherapy and hormonal therapies. Previous studies have shown over-expression of EGFR i...