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Article
Open AccessConstruction of novel multi-epitope-based diagnostic biomarker HP16118P and its application in the differential diagnosis of Mycobacterium tuberculosis latent infection
Tuberculosis (TB) is an infectious disease that significantly threatens human health. However, the differential diagnosis of latent tuberculosis infection (LTBI) and active tuberculosis (ATB) remains a challen...
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Article
Comparison of Fatigue Hydraulic Fracturing of Granite Cores Subjected to Creep and Cyclic Injection
Earlier experiments have shown that cyclic hydraulic fracturing (CHF) systematically reduces the monotonic breakdown pressure (MBP). However, cyclic injection also causes a significantly longer injection time ...
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Article
Open AccessmTOR inhibitor reduces nontumour-related death in liver transplantation for hepatocellular carcinoma
Sirolimus is a regularly applied immunosuppressant for patients undergoing liver transplantation (LT) for hepatocellular carcinoma (HCC). Sirolimus not only significantly inhibits HCC recurrence but also prote...
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Article
Controls on the effect of impact scra** on high-position and long-runout landslides
Landslides in mountainous areas act as an important control on morphological landscape evolution and represent a major natural hazard. The dynamic characteristics of a landslide directly relate to the distance...
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Article
Open AccessCell cycle arrest induces lipid droplet formation and confers ferroptosis resistance
How cells coordinate cell cycling with cell survival and death remains incompletely understood. Here, we show that cell cycle arrest has a potent suppressive effect on ferroptosis, a form of regulated cell dea...
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Article
Open AccessFrom immunology to artificial intelligence: revolutionizing latent tuberculosis infection diagnosis with machine learning
Latent tuberculosis infection (LTBI) has become a major source of active tuberculosis (ATB). Although the tuberculin skin test and interferon-gamma release assay can be used to diagnose LTBI, these methods can...
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Article
Open AccessResearch on the control strategy of DC microgrids with distributed energy storage
As a supplement to large power grids, DC microgrids with new energy access are increasingly widely used. However, with the increasing proportion of new energy in DC microgrids, its output fluctuations directly...
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Article
Open AccessSLC7A11 expression level dictates differential responses to oxidative stress in cancer cells
The cystine transporter solute carrier family 7 member 11 (SLC7A11; also called xCT) protects cancer cells from oxidative stress and is overexpressed in many cancers. Here we report a surprising finding that, ...
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Article
Open AccessHNRNPA2B1-mediated m6A modification of lncRNA MEG3 facilitates tumorigenesis and metastasis of non-small cell lung cancer by regulating miR-21-5p/PTEN axis
Accumulating data indicate that N6-methyladenosine (m6A) RNA methylation and lncRNA deregulation act crucial roles in cancer progression. Heterogeneous nuclear ribonucleoprotein A2B1 (HNRNPA2B1) as an m6A “reader...
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Article
Estimating Earth Pressure during Tunneling in Gravel-cobble Stratum by Considering Sensor-particle Size Effect
When tunneling in gravel-cobble stratum with earth balanced shield, the ratio between the diameters of the pressure sensor embodied in muck chamber and cut gravels is generally small. The small sensor-particle...
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Article
Open AccessNumerical investigation of laboratory hydraulic fracturing tests in Pocheon granite
This study investigates numerically several hydraulic fracturing experiments that were performed on intact cubic Pocheon granite samples applying different injection protocols. The goal of the laboratory exper...
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Article
Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis
SLC7A11-mediated cystine uptake suppresses ferroptosis yet promotes cell death under glucose starvation; the nature of the latter cell death remains unknown. Here we show that aberrant accumulation of intracel...
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Article
Open AccessFrictional stability and permeability evolution of fractures subjected to repeated cycles of heating-and-quenching: granites from the Gonghe Basin, northwest China
Fluid injection into enhanced geothermal system (EGS) reservoirs can reactivate subsurface fractures/faults and trigger earthquakes—requiring that frictional stability and permeability evolution characteristic...
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Article
Open AccessApplication of covalent organic frameworks and metal–organic frameworks nanomaterials in organic/inorganic pollutants removal from solutions through sorption-catalysis strategies
With the fast development of agriculture, industrialization and urbanization, large amounts of different (in)organic pollutants are inevitably discharged into the ecosystems. The efficient decontamination of t...
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Chapter and Conference Paper
Research on the Phygital Innovation Path of the Art Museums Based on Public Participation
As an important place for public art aesthetics and art education, art museums increasingly emphasize the importance of public participation. Phygital in the paper is a compound word, which is composed of Phys...
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Article
Shewanella shenzhenensis sp. nov., a novel Fe(III)-reducing bacterium with abundant possible cytochrome genes, isolated from mangrove sediment
A facultative anaerobic bacterium, designated as A25T, was isolated from a mangrove sediment sample collected in Shenzhen, China. Cells of strain A25T were found to be Gram-staining negative, rod-shaped, flagella...
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Article
Open AccessA novel method for estimating subresolution porosity from CT images and its application to homogeneity evaluation of porous media
We propose a new method, i.e., the statistical phase fraction (SPF) method, to estimate the total porosity and spatial distribution of local porosities from subresolution pore-dominated X-ray microtomography i...
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Article
Open AccessApplication of biochar-based photocatalysts for adsorption-(photo)degradation/reduction of environmental contaminants: mechanism, challenges and perspective
The fast increase of population results in the quick development of industry and agriculture. Large amounts of contaminants such as metal ions and organic contaminants are released into the natural environment...
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Article
Targeting ferroptosis as a vulnerability in cancer
Ferroptosis is an iron-dependent form of regulated cell death that is triggered by the toxic build-up of lipid peroxides on cellular membranes. In recent years, ferroptosis has garnered enormous interest in ca...
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Article
Open AccessFerroptosis as an important driver of lupus
