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Article
Structures of the ADGRG2–Gs complex in apo and ligand-bound forms
Adhesion G protein-coupled receptors are elusive in terms of their structural information and ligands. Here, we solved the cryogenic-electron microscopy (cryo-EM) structure of apo-ADGRG2, an essential membrane...
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Article
A method for obtaining dynamic spectrum based on the proportion of multi-wavelength PPG waveform and applying it to noninvasive detection of human platelet content
Dynamic spectroscopy (DS) theoretically eliminates individual differences and the impact of measurement conditions on accuracy and can achieve high-precision noninvasive blood component analysis. To further im...
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Article
Rapid segmentation and sensitive analysis of CRP with paper-based microfluidic device using machine learning
Microfluidic paper-based analytical devices (μPADs) have been widely used in point-of-care testing owing to their simple operation, low volume of the sample required, and the lack of the need for an external f...
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Article
Antibiofilm Activity of Allicin and Quercetin in Treating Biofilm-Associated Orthopaedics Infection
Biofilms formed by bacteria are the group of sessile microbial cells that remain encompassed by self-secreted polymeric substances and have resulted in great health-care concern. The extracellular polymeric su...
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Article
Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis
Spindle position control is essential for cell fate determination and organogenesis. Early studies indicate the essential role of the evolutionarily conserved Gαi/LGN/NuMA network in spindle positioning. Howev...
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Article
Coupling N2 and CO2 in H2O to synthesize urea under ambient conditions
The use of nitrogen fertilizers has been estimated to have supported 27% of the world’s population over the past century. Urea (CO(NH2)2) is conventionally synthesized through two consecutive industrial processes...
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Article
Ultra-stable D-shaped Optical Fiber Refractive Index Sensor with Graphene-Gold Deposited Platform
In this paper, we demonstrate a high sensitivity refractive index (RI) sensor with D-shaped structure covered with gold and graphene film. Specifically, the effect of structural parameters on the stability of ...
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Article
Syntheses and crystal structure of copper (II) and cobalt (II) complexes containing N-heterocyclic compounds
Four Cu(II) and Co(II) complexes with N-containing heterocycles as ligands were reported firstly. In a simple method, the reaction of 2-benzenediacetonitrile and pyridine-2-carboxaldehyde 2-quinolylhydrazone w...
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Article
Photocurrent Enhancement in Si-Ge Photodetectors by Utilizing Surface Plasmons
A circular slit-groove surface plasmon polaritons (SPPs) launcher surrounding a photodetector is employed theoretically to enhance the photocurrent of atypical Si-Ge photodetectors. The slit and grooves are de...
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Article
Magnetic iron oxide modified pyropheophorbide-a fluorescence nanoparticles as photosensitizers for photodynamic therapy against ovarian cancer (SKOV-3) cells
Magnetic iron oxide modified pyropheophorbide-a fluorescence nanoparticles, Fe3O4@SiO2@APTES@PPa (FSAP), were designed as magnetically targeted photodynamic antineoplastic agents and prepared through continuous c...
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Article
Experimental realization of two-dimensional boron sheets
A variety of two-dimensional materials have been reported in recent years, yet single-element systems such as graphene and black phosphorus have remained rare. Boron analogues have been predicted, as boron ato...
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Article
Dynamically Tunable Plasmonic Lens between the Near and Far Fields Based on Composite Nanorings Illuminated with Radially Polarized Light
We present a plasmonic lens with a dynamically tunable focal length in the mid-infrared region that is composed of gold film with annular slits and embedded vanadium dioxide (VO2) nanorings. When illuminated with...
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Article
Preparation and Testing of Quaternized Chitosan Nanoparticles as Gene Delivery Vehicles
The aim of this study was to synthesize a chitosan (CS) derivative, a quaternary ammonium salt crystal called N-2-hydroxypropyl trimethyl ammonium chloride chitosan (HACC), and test a series of HACC and pEGFP-...
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Article
Biotransformation of 1,3-Propanediol Cyclic Sulfate and Its Derivatives to Diols by Toluene-Permeabilized Cells of Bacillus sp. CCZU11-1
In this study, it was the first report that Bacillus sp. CCZU11-1 was used for the biotransformation of 1,3-propanediol cyclic sulfate (1,3-PDS) and its derivatives. The catalytic performance of Bacillus sp. sulf...
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Article
Primary culture of human face skin melanocytes for the study of hyperpigmentation
Facial epidermal pigmentation and skin tumors can be caused by UV exposure and other physical and chemical irritations. In this report we describe the primary culture of melanocytes from human face skin. The a...
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Article
Optimized and efficient preparation of astrocyte cultures from rat spinal cord
Astrocytes constitute a major class of glial cells in the CNS, and play crucial roles in physiological functioning, performance and maintenance of the CNS, as well as promotion of neuronal migration and matura...
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Article
Methyl jasmonate stimulates jaceosidin and hispidulin production in cell cultures of Saussurea medusa
Cell cultures of Saussurea medusa produce valuable secondary metabolites, and jaceosidin and hispidulin are the major bioactive compounds. In the present study, the cultures were challenged by methyl jasmonate (M...
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Article
Determination of thiol compounds in rat striatum microdialysate by HPLC with a nanosized CoHCF-modified electrode
A cobalt hexacyanoferrate (CoHCF) nanoparticle (size ca. 60 nm) chemically modified electrode (CME) was fabricated and the electrochemical behavior of thiols at this nanosized CoHCF CME was studied. In compari...