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Open AccessNociceptor neurons affect cancer immunosurveillance
Solid tumours are innervated by nerve fibres that arise from the autonomic and sensory peripheral nervous systems1–5. Whether the neo-innervation of tumours by pain-initiating sensory neurons affects cancer immun...
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Article
Author Correction: Widespread long-range cis-regulatory elements in the maize genome
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Widespread long-range cis-regulatory elements in the maize genome
Genetic map** studies on crops suggest that agronomic traits can be controlled by gene–distal intergenic loci. Despite the biological importance and the potential agronomic utility of these loci, they remain...
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Article
Open AccessRational development of transformation in Clostridium thermocellum ATCC 27405 via complete methylome analysis and evasion of native restriction–modification systems
A major barrier to both metabolic engineering and fundamental biological studies is the lack of genetic tools in most microorganisms. One example is Clostridium thermocellum ATCC 27405T, where genetic tools are n...
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Article
Multiple genes recruited from hormone pathways partition maize diterpenoid defences
Duplication and divergence of primary pathway genes underlie the evolution of plant specialized metabolism; however, mechanisms partitioning parallel hormone and defence pathways are often speculative. For exa...
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Article
Open AccessTET-mediated epimutagenesis of the Arabidopsis thaliana methylome
DNA methylation in the promoters of plant genes sometimes leads to transcriptional repression, and the loss of DNA methylation in methyltransferase mutants results in altered gene expression and severe develop...
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Article
Open AccessThe evolution of CHROMOMETHYLASES and gene body DNA methylation in plants
The evolution of gene body methylation (gbM), its origins, and its functional consequences are poorly understood. By pairing the largest collection of transcriptomes (>1000) and methylomes (77) across Viridipl...
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Article
Open AccessDynamic changes in the transcriptome of Populus hopeiensis in response to abscisic acid
Abscisic acid (ABA) plays a fundamental role in plant response and adaptation to abiotic stresses, such as drought, high salinity and low temperature. Populus hopeiensis exhibits exceptional tolerance to water-de...
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Open AccessWidespread natural variation of DNA methylation within angiosperms
DNA methylation is an important feature of plant epigenomes, involved in the formation of heterochromatin and affecting gene expression. Extensive variation of DNA methylation patterns within a species has bee...
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Article
Open AccessFull-length autonomous transposable elements are preferentially targeted by expression-dependent forms of RNA-directed DNA methylation
Chromatin modifications such as DNA methylation are targeted to transposable elements by small RNAs in a process termed RNA-directed DNA methylation (RdDM). In plants, canonical RdDM functions through RNA poly...
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Article
Identification of glutathione S-transferase genes responding to pathogen infestation in Populus tomentosa
Stem blister canker, caused by Botryosphaeria dothidea, is becoming the most serious disease of poplar in China. The molecular basis of the poplar in response to stem blister canker is not well understood. To rev...
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Open AccessStudy of seed hair growth in Populus tomentosa, an important character of female floral bud development
Poplar seed hair is an environmental annoyance in northern China due to its abundance and widespread airborne distribution after maturation. The morphogenesis and molecular mechanisms of its development are no...
