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    Chapter and Conference Paper

    Strategies to Inhibit the Toxicity of Systemic TNF Treatment

    Research in our unit has focused on several aspects of acute inflammatory shock induced by pro-inflammatory molecules, such as the cytokines TNF and IL-1, and the bacterial cell wall component, LPS. We have pa...

    Filip Van Hauwermeiren, Leen Puimège, Sofie Vandevyver in Advances in TNF Family Research (2011)

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    Article

    Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders

    Most inflammatory disorders are becoming more prevalent, especially in Western countries. The proinflammatory cytokine tumor necrosis factor-α (TNF) plays a prominent role in many of these inflammatory disorde...

    Jan Staelens, Leen Puimège, Tina Mahieu, Gwenda Pynaert, Tino Hochepied in Mammalian Genome (2004)