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  1. Article

    Open Access

    Improved cytosine base editors generated from TadA variants

    Cytosine base editors (CBEs) enable programmable genomic C·G-to-T·A transition mutations and typically comprise a modified CRISPR–Cas enzyme, a naturally occurring cytidine deaminase, and an inhibitor of uraci...

    Dieter K. Lam, Patricia R. Feliciano, Amena Arif, Tanggis Bohnuud… in Nature Biotechnology (2023)

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    Article

    Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification

    Neoantigen prediction from clinical samples is improved using a neural network model trained on a large HLA peptide and genomic tumor dataset.

    Brendan Bulik-Sullivan, Jennifer Busby, Christine D Palmer… in Nature Biotechnology (2019)