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  1. No Access

    Chapter and Conference Paper

    The C3C Game: Serious Games and Community-Centered Design for Improved Pandemic Decision Making

    Serious games have long been used in domains like defense, management, finance, and environmental protection to improve plans and procedures. In the aftermath of the COVID-19 pandemic, public health and emerge...

    Francesca de Rosa, Mark Escott, Douglas Havron in Games and Learning Alliance (2024)

  2. Article

    Open Access

    Evaluation of the US COVID-19 Scenario Modeling Hub for informing pandemic response under uncertainty

    Our ability to forecast epidemics far into the future is constrained by the many complexities of disease systems. Realistic longer-term projections may, however, be possible under well-defined scenarios that s...

    Emily Howerton, Lucie Contamin, Luke C. Mullany, Michelle Qin in Nature Communications (2023)

  3. Article

    Open Access

    Real time monitoring of COVID-19 intervention effectiveness through contact tracing data

    Communities worldwide have used vaccines and facemasks to mitigate the COVID-19 pandemic. When an individual opts to vaccinate or wear a mask, they may lower their own risk of becoming infected as well as the ...

    Graham C. Gibson, Spencer Woody, Emily James, Minda Weldon in Scientific Reports (2023)

  4. Article

    Open Access

    Design of COVID-19 staged alert systems to ensure healthcare capacity with minimal closures

    Community mitigation strategies to combat COVID-19, ranging from healthy hygiene to shelter-in-place orders, exact substantial socioeconomic costs. Judicious implementation and relaxation of restrictions ampli...

    Haoxiang Yang, Özge Sürer, Daniel Duque, David P. Morton in Nature Communications (2021)

  5. Article

    Selecting pharmacies for COVID-19 testing to ensure access

    Rapid diagnostic testing for COVID-19 is key to guiding social distancing orders and containing emerging disease clusters by contact tracing and isolation. However, communities throughout the US do not yet hav...

    Simon Risanger, Bismark Singh, David Morton in Health Care Management Science (2021)

  6. Article

    Open Access

    Modeling mitigation of influenza epidemics by baloxavir

    Influenza viruses annually kill 290,000–650,000 people worldwide. Antivirals can reduce death tolls. Baloxavir, the recently approved influenza antiviral, inhibits initiation of viral mRNA synthesis, whereas o...

    Zhanwei Du, Ciara Nugent, Alison P. Galvani, Robert M. Krug in Nature Communications (2020)

  7. Article

    Open Access

    Couple serostatus patterns in sub-Saharan Africa illuminate the relative roles of transmission rates and sexual network characteristics in HIV epidemiology

    HIV prevalence has surpassed 30% in some African countries while peaking at less than 1% in others. The extent to which this variation is driven by biological factors influencing the HIV transmission rate or b...

    Steven E. Bellan, David Champredon, Jonathan Dushoff in Scientific Reports (2018)

  8. Article

    Open Access

    The cost-effectiveness of oral HIV pre-exposure prophylaxis and early antiretroviral therapy in the presence of drug resistance among men who have sex with men in San Francisco

    Poor adherence to either antiretroviral treatment (ART) or pre-exposure prophylaxis (PrEP) can promote drug resistance, though this risk is thought to be considerably higher for ART. In the population of men w...

    Mingwang Shen, Yanni **ao, Libin Rong, Lauren Ancel Meyers in BMC Medicine (2018)

  9. Article

    Open Access

    Estimation of single-year-of-age counts of live births, fetal losses, abortions, and pregnant women for counties of Texas

    We provide a methodology for estimating counts of single-year-of-age live-births, fetal-losses, abortions, and pregnant women from aggregated age-group counts. As a case study, we estimate counts for the 254 c...

    Bismark Singh, Lauren Ancel Meyers in BMC Research Notes (2017)

  10. Article

    Open Access

    Assessing real-time Zika risk in the United States

    Confirmed local transmission of Zika Virus (ZIKV) in Texas and Florida have heightened the need for early and accurate indicators of self-sustaining transmission in high risk areas across the southern United S...

    Lauren A. Castro, Spencer J. Fox, ** Chen, Kai Liu in BMC Infectious Diseases (2017)

  11. Article

    Open Access

    Enhancing disease surveillance with novel data streams: challenges and opportunities

    Novel data streams (NDS), such as web search data or social media updates, hold promise for enhancing the capabilities of public health surveillance. In this paper, we outline a conceptual framework for integr...

    Benjamin M Althouse, Samuel V Scarpino, Lauren Ancel Meyers in EPJ Data Science (2015)

  12. Article

    Erratum to: Impact of Imitation Processes on the Effectiveness of Ring Vaccination

    Chad R. Wells, Jean M. Tchuenche, Lauren Ancel Meyers in Bulletin of Mathematical Biology (2014)

  13. Article

    Open Access

    Simulating school closure policies for cost effective pandemic decision making

    Around the globe, school closures were used sporadically to mitigate the 2009 H1N1 influenza pandemic. However, such closures can detrimentally impact economic and social life.

    Ozgur M Araz, Paul Damien, David A Paltiel, Sean Burke in BMC Public Health (2012)

  14. Article

    Open Access

    EpiFire: An open source C++ library and application for contact network epidemiology

    Contact network models have become increasingly common in epidemiology, but we lack a flexible programming framework for the generation and analysis of epidemiological contact networks and for the simulation o...

    Thomas Hladish, Eugene Melamud, Luis Alberto Barrera, Alison Galvani in BMC Bioinformatics (2012)

  15. Article

    Open Access

    Vaccination against 2009 pandemic H1N1 in a population dynamical model of Vancouver, Canada: timing is everything

    Much remains unknown about the effect of timing and prioritization of vaccination against pandemic (pH1N1) 2009 virus on health outcomes. We adapted a city-level contact network model to study different campai...

    Jessica M Conway, Ashleigh R Tuite, David N Fisman, Nathaniel Hupert in BMC Public Health (2011)

  16. Article

    Impact of Imitation Processes on the Effectiveness of Ring Vaccination

    Ring vaccination can be a highly effective control strategy for an emerging disease or in the final phase of disease eradication, as witnessed in the eradication of smallpox. However, the impact of behavioural...

    Chad R. Wells, Jean M. Tchuenche, Lauren Ancel Meyers in Bulletin of Mathematical Biology (2011)

  17. Article

    Open Access

    Optimal H1N1 vaccination strategies based on self-interest versus group interest

    Influenza vaccination is vital for reducing H1N1 infection-mediated morbidity and mortality. To reduce transmission and achieve herd immunity during the initial 2009-2010 pandemic season, the US Centers for Di...

    Eunha Shim, Lauren Ancel Meyers, Alison P Galvani in BMC Public Health (2011)

  18. Article

    Open Access

    Exploring biological network structure with clustered random networks

    Complex biological systems are often modeled as networks of interacting units. Networks of biochemical interactions among proteins, epidemiological contacts among hosts, and trophic interactions in ecosystems,...

    Shweta Bansal, Shashank Khandelwal, Lauren Ancel Meyers in BMC Bioinformatics (2009)

  19. No Access

    Article

    The Robustness of Naturally and Artificially Selected Nucleic Acid Secondary Structures

    Thermodynamic stability and mutational robustness of secondary structure are critical to the function and evolutionary longevity of RNA molecules. We hypothesize that natural and artificial selection for funct...

    Lauren Ancel Meyers, Jennifer F. Lee in Journal of Molecular Evolution (2004)