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Open AccessTrade-offs sha** transmission of sylvatic dengue and Zika viruses in monkey hosts
Mosquito-borne dengue (DENV) and Zika (ZIKV) viruses originated in Old World sylvatic (forest) cycles involving monkeys and canopy-living Aedes mosquitoes. Both viruses spilled over into human transmission and we...
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Open AccessThe unintended consequences of inconsistent closure policies and mobility restrictions during epidemics
Controlling the spread of infectious diseases―even when safe, transmission-blocking vaccines are available―may require the effective use of non-pharmaceutical interventions (NPIs), e.g., mask wearing, testing,...
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Article
Open AccessImpact of SARS-CoV-2 Gamma lineage introduction and COVID-19 vaccination on the epidemiological landscape of a Brazilian city
The emergence of the Brazilian variant of concern, Gamma lineage (P.1), impacted the epidemiological profile of COVID-19 cases due to its higher transmissibility rate and immune evasion ability.
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A review and agenda for integrated disease models including social and behavioural factors
Social and behavioural factors are critical to the emergence, spread and containment of human disease, and are key determinants of the course, duration and outcomes of disease outbreaks. Recent epidemics of Eb...
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Open AccessDifferences in clinical severity of respiratory viral infections in hospitalized children
It is uncertain whether clinical severity of an infection varies by pathogen or by multiple infections. Using hospital-based surveillance in children, we investigate the range of clinical severity for patients...
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Open AccessRole of monkeys in the sylvatic cycle of chikungunya virus in Senegal
Arboviruses spillover into humans either as a one-step jump from a reservoir host species into humans or as a two-step jump from the reservoir to an amplification host species and thence to humans. Little is k...
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The Charlie Sheen Effect on Rapid In-home Human Immunodeficiency Virus Test Sales
One in eight of the 1.2 million Americans living with human immunodeficiency virus (HIV) are unaware of their positive status, and untested individuals are responsible for most new infections. As a result, tes...
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The Role of Fear-Related Behaviors in the 2013–2016 West Africa Ebola Virus Disease Outbreak
The 2013–2016 West Africa Ebola virus disease pandemic was the largest, longest, deadliest, and most geographically expansive outbreak in the 40-year interval since Ebola was first identified. Fear-related beh...
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Open AccessEnhancing disease surveillance with novel data streams: challenges and opportunities
Novel data streams (NDS), such as web search data or social media updates, hold promise for enhancing the capabilities of public health surveillance. In this paper, we outline a conceptual framework for integr...
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Open AccessAsymptomatic transmission and the resurgence of Bordetella pertussis
The recent increase in whoo** cough incidence (primarily caused by Bordetella pertussis) presents a challenge to both public health practitioners and scientists trying to understand the mechanisms behind its re...