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Article
Randomized clinical trial to comparing efficacy of daily, weekly and monthly administration of vitamin D3
The comparative efficacy and safety profiles of selected daily 1000 IU, weekly 7000 IU and monthly 30,000 IU vitamin D 3—not previously investigated—will be evaluated. Here, a prospective,...
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Article
The role of serum total and free 25-hydroxyvitamin D and PTH values in defining vitamin D status at the end of winter: a representative survey
We sought the lowest serum total 25-hydroxyvitamin D (t-25OHD) values in geographic areas with four seasons and investigated whether the calculation of serum free 25-hydroxyvitamin D (f-25OHD) could provide ad...
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Protocol
Delayed Protection of the Myocardium
It is known that the administration of drugs can relieve or prevent many of the consequences of myocardial ischemia; this is the basis for the current therapy of angina of effort by, for example, organic nitri...
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Chapter
Long-Term but not Short-Term Cardioprotection can be Induced by Preconditioning in Hypercholesterolemia
Preconditioning of the heart by single or multiple noninjurious ischemic stimuli may induce both short-term (up to 2 hours) and long-term (3 to 24–48 hours) cardiac protection against the consequences of a sub...
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Article
Prevention by 7-oxo-prostacyclin of the calcium paradox in rat heart: Role of the sarcolemmal (Na,K)-ATPase
It is demonstrated a fast and significant depression in the sarcolemmal (Na,K)-ATPase activity that occurs as early as 25 sec after the onset of Ca2+ depletion, and participates in the development of Ca2+-paradox...
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Chapter
Prevention by 7-oxo-prostacyclin of the calcium paradox in rat heart: Role of the sarcolemmal (Na,K)-ATPase
It is demonstrated a fast and significant depression in the sarcolemmal (Na,K)-ATPase activity that occurs as early as 25 sec after the onset of Ca2+ depletion, and participates in the development of Ca2+-paradox...
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Article
On the mechanism and possible therapeutic application of delayed adaptation of the heart to stress situations
Mild (not harmful) stress may initiate anadaptive mechanism, protecting the heart from harmful consequences of a more severe stress. There are at least three known types of cardiac adaptation to stress such as:
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Chapter
On the mechanism and possible therapeutic application of delayed adaptation of the heart to stress situations
Mild (not harmful) stress may initiate an adaptive mechanism, protecting the heart from harmful consequences of a more severe stress. There are at least three known types of cardiac adaptation to stress, such as:...
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Article
Long lasting anti-adrenergic effect of 7-oxo-prostacyclin in the heart: a cycloheximide sensitive increase of phosphodiesterase isoform I and IV activities
Evidence is accumulating that 7-oxo-prostacyclin (7-oxo-PGI2) induces a delayed indirect anti-adrenergic and cytoprotective effect on the myocardium, the mechanism of which is still unclear. To demonstrate that a...
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Article
Release of 6-KETO-PGF1α and thromboxane B2 in late appearing cardioprotection induced by the stable PGI analogue: 7-OXO-PGI
We have shown earlier that prostacylin (PGI2) and its stable analogue: 7-oxo-prostacyclin(7-OXO) may induce a prolonged, late appearing (24–48 h after drug administration), dose dependent protection of the heart ...
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Chapter
Release of 6-KET0-PGFlα and thromboxane B2 in late appearing cardioprotection induced by the stable PGI analogue: 7-OXO-PGI
We have shown earlier that prostacyclin (PGI2) and its stable analogue: 7-oxo-prostacyclin(7-OXO) may induce a prolonged, late appearing (24–48 h after drug administration), dose dependent protection of the heart...
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Chapter
Preconditioning: An Early Protective Response to Myocardial Ischaemia
Recently there has been a great deal of interest in the concept that myocardial cells are capable of rapidly adapting to brief periods of stress, such as ischaemia, in a manner that is protective against longe...
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Article
Spectrophotometric determination of salicylamide in complex mixtures
This paper describes a spectrophotometric assay procedure for the determination of small amounts of salicylamide in the presence of a variety of foreign substances, including salicylates and acetaminophenol.
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Article
Bestimmung der Perjodat-, Jodat-, Bromat- und Chlorationen nebeneinander
Bei dem beschriebenen Verfahren zur Analyse eines Gemisches von Perjodat, Jodat, Bromat und Chlorat sind vier jodometrische Titrationen notwendig, die in vier aliquoten Teilen der zu untersuchenden Lösung durc...
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Article
Die Bestimmung der Bromat- und Perjodationen nebeneinander
Für die Bestimmung von Bromat- und Perjodationen nebeneinander werden zwei Verfahren beschrieben.