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    Article

    Antioxidant proteins and reactive oxygen species are decreased in a murine epidermal side population with stem cell-like characteristics

    Reactive oxygen species (ROS) and antioxidants are essential to maintain a redox balance within tissues and cells. Intracellular ROS regulate key cellular functions such as proliferation, differentiation and a...

    Wanakee J. Carr, Rebecca E. Oberley-Deegan, Yu** Zhang… in Histochemistry and Cell Biology (2011)

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    Chapter

    The Adventures of Superoxide Dismutase in Health and Disease: Superoxide in the Balance

    This chapter focuses on superoxide dismutases (SOD), a group of enzymes important for removing biologically generated superoxide anion radical (O2 .−). These enzymes function by catalyzing th...

    Kristy M. Powers, Larry W. Oberley, Frederick E. Domann in Oxidants in Biology (2008)

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    Article

    Metastatic Progression of Pancreatic Cancer: Changes in Antioxidant Enzymes and Cell Growth

    Pancreatic cancer has a dismal prognosis due to the fact that patients present late when metastatic disease is already present. Previous studies have demonstrated that pancreatic cancer cells have decreased le...

    Anne Lewis, Juan Du, **gru Liu, Justine M. Ritchie… in Clinical & Experimental Metastasis (2005)

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    Article

    Overexpression of Glia Maturation Factor in C6 Cells Promotes Differentiation and Activates Superoxide Dismutase

    In order to evaluate the intracellular function of glia maturation factor (GMF), we overexpressed GMF in C6 rat glioma cells using two methods: stable transfection using the pcDNA3 plasmid, and transient trans...

    Ramon Lim, Asgar Zaheer, Jeff A. Kraakevik, Christine J. Darby… in Neurochemical Research (1998)

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    Article

    Immunohistochemical characterization of antioxidant enzymes in human breast cancer

    Intrinsic antioxidant enzymes (AE) are essential for protection against potential cellular damage by free radicals (FRs), which affect a variety of biological processes. The levels or activities of AEs can be ...

    Patricia A Thomas, Dilek Oykutlu, Bel Pou, Denise Tyler… in Pathology & Oncology Research (1997)

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    Article

    Anticancer activity of metal compounds with superoxide dismutase activity

    Larry W. Oberley, S. W. C. Leuthauser, Robert F. Pasternack… in Agents and Actions (1984)