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Article
Method for the generation and cultivation of functional three-dimensional mammary constructs without exogenous extracellular matrix
During puberty, pregnancy, lactation and post-lactation, breast tissue undergoes extensive remodelling and the disruption of these events can lead to cancer. In vitro studies of mammary tissue and its malignan...
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Chapter and Conference Paper
Effects of Multiplicity of Infection (MOI) and Cell Cycle on Baculovirus Infection Kinetics
Synchronously infected cells show a large spread in the timing of cell death. This asynchrony is caused neither by the number of viruses a cell receives nor by the cell cycle status of the cell at the time of ...
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Article
Population balance model of in vivo neutrophil formation following bone marrow rescue therapy
In this paper, we develop a simple four parameter population balance model of in vivo neutrophil formation following bone marrow rescue therapy. The model is used to predict the number and type of neutrophil p...
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Chapter
Population balance model of in vivo neutrophil formation following bone marrow rescue therapy
In this paper, we develop a simple four parameter population balance model of in vivo neutrophil formation following bone marrow rescue therapy. The model is used to predict the number and type of neutrophil prog...
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Article
Lake restoration using a reed swamp to remove nutrients from non-point sources
The reed swamp adjacent to Lake Glumsø was partly separated from the lake by a dam and the inflow to the reed swamp controlled by pum** from the tributary. An investigation of the nutrient balances for the r...
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Chapter
Using Oxygen Uptake Rates to Time Infections in the Baculovirus Expression Vector System
In this article, the problem of optimising insect cell cultures infected with a recombinant Baculovirus is discussed. A model of the infection of insect cells in batch cultures suggests that the maximum achiev...
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Chapter
Improved Monoclonal Antibody Production via Controlled Feeding Strategies during Fedbatch Cultures of a Hybridoma Cell Line Utilizing Protein Free Media
A quantitative study on the effect of feed concentration and feed rate during a fedbatch cultivation system on the performance of the SPO1 hybridoma cell line using a protein free media is presented. The objec...
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Article
Avoiding rapid growth at high cell densities: A potentially important optimisation criterion for hybridoma cultures
Inhibition caused by rapid changes in the environment has earlier been observed in hybridoma cultures following deliberate step-changes in the culture environment. This paper presents evidence of similar effec...
