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  1. Article

    Open Access

    Retargeted adenoviruses for radiation-guided gene delivery

    The combination of radiation with radiosensitizing gene delivery or oncolytic viruses promises to provide an advantage that could improve the therapeutic results for glioblastoma. X-rays can induce significant...

    S A Kaliberov, L N Kaliberova, H Yan, V Kapoor, D E Hallahan in Cancer Gene Therapy (2016)

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    Article

    Experimental virotherapy of chemoresistant pancreatic carcinoma using infectivity-enhanced fiber-mosaic oncolytic adenovirus

    Pancreatic cancer is a significant clinical problem and novel therapeutic approaches are desperately needed. Recent advances in conditionally replicative adenovirus-based (CRAd) oncolytic virus design allow th...

    S A Kaliberov, L N Kaliberova, D J Buchsbaum, D T Curiel in Cancer Gene Therapy (2014)

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    Article

    CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma

    Malignant forms of glioma, the most common primary brain tumors, remain poorly responsive to multimodality therapeutic interventions, including chemotherapy. Suppressed apoptosis and extraordinary invasiveness...

    L N Kaliberova, V Krendelchtchikova, D K Harmon, C R Stockard… in Cancer Gene Therapy (2009)

  4. Article

    Erratum: Mutation of Escherichia coli cytosine deaminase significantly enhances molecular chemotherapy of human glioma

    Correction to: Gene Therapy (2008) 14, 1111–1119; doi:10.1038/sj.gt.3302965 Since the above publication, the authors have noticed that JM Markert's name was published incorrectly. The correct name is shown abo...

    S A Kaliberov, J M Markert, G Y Gillespie, V Krendelchtchikova… in Gene Therapy (2008)

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    Article

    Mutation of Escherichia coli cytosine deaminase significantly enhances molecular chemotherapy of human glioma

    Combined treatment using adenoviral (Ad)-directed enzyme/prodrug therapy and radiation therapy has the potential to become a powerful method of cancer therapy. We have developed an Ad vector encoding a mutant ...

    S A Kaliberov, J M Market, G Y Gillespie, V Krendelchtchikova… in Gene Therapy (2007)

  6. No Access

    Article

    Combination of cytosine deaminase suicide gene expression with DR5 antibody treatment increases cancer cell cytotoxicity

    Combined treatment using adenoviral-directed enzyme/prodrug therapy and immunotherapy has the potential to become a powerful alternative method of cancer therapy. We have developed adenoviral vectors encoding ...

    S A Kaliberov, S Chiz, L N Kaliberova, V Krendelchtchikova… in Cancer Gene Therapy (2006)

  7. No Access

    Article

    Combined ionizing radiation and sKDR gene delivery for treatment of prostate carcinomas

    Overexpression of vascular endothelial growth factor (VEGF) and its cognate receptor KDR has been linked to a more aggressive phenotype of human prostate carcinomas. The importance of signal transduction throu...

    S A Kaliberov, L N Kaliberova, D J Buchsbaum in Gene Therapy (2005)