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339 Result(s)
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Open AccessAuthor Correction: Deciphering Aphanomyces euteiches-pea-biocontrol bacterium interactions through untargeted metabolomics
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Abnormal cerebral blood flow and brain function in type 2 diabetes mellitus
Type 2 diabetes mellitus (T2DM) lead to impaired cerebral blood perfusion, which leads to changes in brain function and affects the cognitive function of patients. In this study, cerebral blood flow (CBF) was ...
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Open AccessCoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels
Genetic testing is crucial for precision cancer medicine. However, detecting multiple same-site insertions or deletions (indels) is challenging. Here, we introduce CoHIT (Cas12a-based One-for-all High-speed Is...
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Open AccessFBXO7 ubiquitinates PRMT1 to suppress serine synthesis and tumor growth in hepatocellular carcinoma
Cancer cells are often addicted to serine synthesis to support growth. How serine synthesis is regulated in cancer is not well understood. We recently demonstrated protein arginine methyltransferase 1 (PRMT1) ...
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Open AccessPrognostic value of neutrophil-to-lymphocyte ratio change in patients with locally advanced non-small cell lung cancer treated with thoracic radiotherapy
In prior investigations, a correlation was established between patient outcomes in locally advanced non-small cell lung cancer (LA-NSCLC) following thoracic irradiation and parameters, such as pre/post-treatme...
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Open AccessEfficient characterizations of multiphoton states with an ultra-thin optical device
Metasurface enables the generation and manipulation of multiphoton entanglement with flat optics, providing a more efficient platform for large-scale photonic quantum information processing. Here, we show that...
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Open AccesscircCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models
Chronic wounds are a major complication in patients with diabetes. Here, we identify a therapeutic circRNA and load it into small extracellular vesicles (sEVs) to treat diabetic wounds in preclinical models. W...
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Open AccessAssociation between low-density lipoprotein cholesterol levels and serum uric acid to serum creatinine ratio in Chinese male gout patients
This study aimed to evaluate the association between low-density lipoprotein cholesterol (LDL-C) and serum uric acid to serum creatinine (SUA/SCr) ratio in male gout patients at different BMIs. This real-world...
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Open AccessDeciphering Aphanomyces euteiches-pea-biocontrol bacterium interactions through untargeted metabolomics
Aphanomyces euteiches causes root rot in pea, leading to significant yield losses. However, the metabolites involved in this pathosystem have not been thoroughly studied. This study aimed to fill this gap and exp...
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Open AccessUpgrading CO2 to sustainable aromatics via perovskite-mediated tandem catalysis
The directional transformation of carbon dioxide (CO2) with renewable hydrogen into specific carbon-heavy products (C6+) of high value presents a sustainable route for net-zero chemical manufacture. However, it i...
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Open AccessUltra-photostable small-molecule dyes facilitate near-infrared biophotonics
Long-wavelength, near-infrared small-molecule dyes are attractive in biophotonics. Conventionally, they rely on expanded aromatic structures for redshift, which comes at the cost of application performance suc...
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Open AccessComparison of genes involved in brain development: insights into the organization and evolution of the telencephalic pallium
The mechanisms underlying the organization and evolution of the telencephalic pallium are not yet clear.. To address this issue, we first performed comparative analysis of genes critical for the development of...
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Open AccessComplete separation of benzene-cyclohexene-cyclohexane mixtures via temperature-dependent molecular sieving by a flexible chain-like coordination polymer
The separation and purification of C6 cyclic hydrocarbons (benzene, cyclohexene, cyclohexane) represent a critically important but energy intensive process. Develo** adsorptive separation technique to replac...
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Open AccessResearch on mechanical properties of concrete by nano-TiC-BF-fly ash
Ultra-high-rise buildings require high concrete bearing capacity. Ordinary concrete often fails to meet the project requirements. Admixture of admixtures in concrete is a means of solution. Currently, studies ...
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Open AccessKirkendall effect-induced uniform stress distribution stabilizes nickel-rich layered oxide cathodes
Nickel-rich layered oxide cathodes promise ultrahigh energy density but is plagued by the mechanical failure of the secondary particle upon (de)lithiation. Existing approaches for alleviating the structural de...
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Open AccessEffects of weights applied to the apex of a bag-valve-mask and pinch strength on tidal volume: a prospective simulation study
A bag-valve-mask (BVM) is a first aid tool that can easily and quickly provide positive-pressure ventilation in patients with breathing difficulties. The most important aspect of BVM bagging is how closely the...
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Open AccessArtesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis
Obesity, a global health challenge, is a major risk factor for multiple life-threatening diseases, including diabetes, fatty liver, and cancer. There is an ongoing need to identify safe and tolerable therapeut...
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Open AccessOlfactory system structure and function in newly hatched and adult locusts
An important question in neuroscience is how sensory systems change as animals grow and interact with the environment. Exploring sensory systems in animals as they develop can reveal how networks of neurons pr...
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Open AccessOmicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue
Omicron emerged following COVID-19 vaccination campaigns, displaced previous SARS-CoV-2 variants of concern worldwide, and gave rise to lineages that continue to spread. Here, we show that Omicron exhibits inc...
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Open AccessAdaptive tactile interaction transfer via digitally embroidered smart gloves
Human-machine interfaces for capturing, conveying, and sharing tactile information across time and space hold immense potential for healthcare, augmented and virtual reality, human-robot collaboration, and ski...