70 Result(s)

Article

Function of 14-3-3 proteins

Dong-Yan **, Myung Soo Lyu, Christine A. Kozak, Kuan-Teh Jeang in Nature (1996)

Article

Requirement for the second coding exon of Tat in the optimal replication of macrophage-tropic HIV-1

HIV-1 Tat is essential for virus replication and is a potent transactivator of viral gene expression. Evidence suggests that Tat also influences virus infectivity and cytopathicity. Here, we find that the seco...

Christine Neuveut, Robert M. Scoggins, David Camerini… in Journal of Biomedical Science (2003)

Article

Retrovirology and young Turks...

Kuan-Teh Jeang in Retrovirology (2004)

Article

Two discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cells

It is poorly understood why many transforming proteins reportedly enhance both cell growth (transformation) and cell death (apoptosis). At first glance, the ability to transform and the ability to engender apo...

Takefumi Kasai, Kuan-Teh Jeang in Retrovirology (2004)

Article

Specific TATAA and bZIP requirements suggest that HTLV-I Tax has transcriptional activity subsequent to the assembly of an initiation complex

Human T-cell leukemia virus type I (HTLV-I) Tax protein is a transcriptional regulator of viral and cellular genes. In this study we have examined in detail the determinants for Tax-mediated transcriptional ac...

Yick-Pang Ching, Abel CS Chun, King-Tung Chin, Zhi-Qing Zhang… in Retrovirology (2004)

Article

Mohmmar Qadaffi, Open Access, and Retrovirology

Retrovirology has been publishing as an Open Access online journal for approximately six months. In this editorial, I review the reasons for and the advantages of Open Access publishing, update our progress to...

Kuan-Teh Jeang in Retrovirology (2004)

Article

HIV-1 encoded candidate micro-RNAs and their cellular targets

MicroRNAs (miRNAs) are small RNAs of 21–25 nucleotides that specifically regulate cellular gene expression at the post-transcriptional level. miRNAs are derived from the maturation by cellular RNases III of im...

Yamina Bennasser, Shu-Yun Le, Man Lung Yeung, Kuan-Teh Jeang in Retrovirology (2004)

Article

Progress, challenges, and responsibilities in retrovirology

In this editorial, Retrovirology's choice for best basic science "retrovirus paper of the year" and a perspective on challenges and responsibilities facing HIV-1 and HTLV-I research are presented.

Kuan-Teh Jeang in Retrovirology (2005)

Article

Jacov Tal (1940 – 2005): remembrances of a friend

An obituary commemorates the life and works of Jacov Tal.

Gabriel Kaufmann, Kuan-Teh Jeang in Retrovirology (2005)

Article

Retrovirology highlights a quarter century of HTLV-I research

In 1977, Takatsuki and co-workers described in Japan a human malignant disease termed adult T-cell leukemia (ATL). Three years later, in 1980, Gallo and colleagues reported the identification of the first huma...

Kuan-Teh Jeang in Retrovirology (2005)

Article

Life after 45 and before 60: the Retrovirology Prize

Retrovirology announces an annual prize to recognize one outstanding mid-career retrovirologist.

Kuan-Teh Jeang in Retrovirology (2005)

Article

Small philanthropy and big science: the RETROVIROLOGY prize and Stephen P. Goff

Stephen P. Goff wins the 2005 RETROVIROLOGY prize.

Kuan-Teh Jeang in Retrovirology (2005)

Article

Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

The HTLV-1 Tax oncoprotein rapidly induces cytogenetic damage which can be measured by a significant increase in the number of micronuclei (MN) in cells. Tax is thought to have both aneuploidogenic and clastog...

Franca Majone, Roberto Luisetto, Daniela Zamboni, Yoichi Iwanaga… in Retrovirology (2005)

Article

Viral and cellular RNA helicases as antiviral targets

Article

siRNA, miRNA and HIV: promises and challenges

Small interfering RNA (siRNA) and microRNA (miRNA) are small RNAs of 18-25 nucleotides (nt) in length that play important roles in regulating gene expression. They are incorporated into an RNA-induced silencin...

Man Lung YEUNG, Yamina BENNASSER, Shu Yun LE, Kuan Teh JEANG in Cell Research (2005)

Article

The value of Institute of Human Virology meeting abstracts and beyond

This month Retrovirology publishes the meeting abstracts from the 10^th annual Institute of Human Virology conference held August 29^th to September 2^nd, 2005 in Baltimore, Maryland, USA. In this editorial, the rat...

Kuan-Teh Jeang in Retrovirology (2005)

Article

Changes in microRNA expression profiles in HIV-1-transfected human cells

MicroRNAs (miRNAs) are small RNAs of 18–25 nucleotides (nt) in length that play important roles in regulating a variety of biological processes. Recent studies suggest that cellular miRNAs may serve to control...

Man Lung Yeung, Yamina Bennasser, Timothy G Myers, Guojian Jiang… in Retrovirology (2005)

Article

A peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlap** reading frames

CTL based vaccine strategies in the macaque model of AIDS have shown promise in slowing the progression to disease. However, rapid CTL escape viruses can emerge rendering such vaccination useless. We hypothesi...

Zachary Klase, Michael J Donio, Andrew Blauvelt, Preston A Marx… in Retrovirology (2006)

Article

The 2006 RetrovirologyPrize: call for nominations

Retrovirology announces a nomination call for its 2006 prize to recognize an outstanding mid-career retrovirologist. The 2005 Retrovirology prize was awarded to Dr. Stephen P. Goff.

Kuan-Teh Jeang in Retrovirology (2006)

Article

Retrovirology: 3 at age 2

Retrovirology announces new editorial board members and reprises progress over the first two years of publishing.

Kuan-Teh Jeang in Retrovirology (2006)