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Chapter
Cancer Angiogenesis and Its Master Regulator Perlecan
Angiogenesis and vasculogenesis are not only indispensable for normal tissue growth and regeneration but also particularly vital for tumors. As without sufficient blood supply that provides nutrients, tumor ce...
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Chapter
The Role of Decorin in Cancer
The dynamic interactions between the tumor cells and their microenvironment consisting of stroma cells and extracellular matrix play a crucial role in cancer development. Decorin, a chondroitin sulfate/dermata...
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Chapter
The Mystery of Syndecan-1 in Tumor Development and Progression
Syndecan-1, a cell surface heparan sulfate proteoglycan, participates in a multitude of cellular processes, and it acts as a “fine tuner of cellular signaling.” Syndecan-1 is present in most epithelial tissues...
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Chapter
Decorin in the Tumor Microenvironment
The tumor microenvironment plays a determining role in cancer development through a plethora of interactions between the extracellular matrix and tumor cells. Decorin is a prototype member of the SLRP family f...
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Article
Antitumoral effects of 9-cis retinoic acid in adrenocortical cancer
The currently available medical treatment options of adrenocortical cancer (ACC) are limited. In our previous meta-analysis of adrenocortical tumor genomics data, ACC was associated with reduced retinoic acid ...
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Article
Triiodothyronine accelerates differentiation of rat liver progenitor cells into hepatocytes
The 2-acetaminofluorene/partial hepatectomy (AAF/Phx) model is widely used to induce oval/progenitor cell proliferation in the rat liver. We have used this model to study the impact of a primary hepatocyte mit...