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  1. Article

    Open Access

    Culture-space control is effective in promoting haploid cell formation and spermiogenesis in vitro in neonatal mice

    The classical organ culture method, in which tissue is placed at the gas‒liquid interphase, is effective at inducing mouse spermatogenesis. However, due to reginal variations in the supply of oxygen and nutrie...

    Kiyoshi Hashimoto, Hisakazu Odaka, Yu Ishikawa-Yamauchi, Shino Nagata in Scientific Reports (2023)

  2. Article

    Open Access

    Generation of rat offspring using spermatids produced through in vitro spermatogenesis

    An in vitro spermatogenesis method using mouse testicular tissue to produce fertile sperm was established more than a decade ago. Although this culture method has generally not been effective in other animal s...

    Takafumi Matsumura, Kumiko Katagiri, Tatsuma Yao in Scientific Reports (2023)

  3. No Access

    Article

    Long-term functional outcome after untethering surgery for a tethered spinal cord in patients with anorectal malformations

    Anorectal malformation (ARM) is associated with a tethered spinal cord (TSC). Long-term functional outcome of untethering surgery for TSC in patients with ARM has not been well evaluated.

    Mikihiro Inoue, Keiichi Uchida, Kohei Otake, Yuka Nagano in Pediatric Surgery International (2017)

  4. No Access

    Article

    Parsing human skeletons in an operating room

    Multiple human pose estimation is an important yet challenging problem. In an operating room (OR) environment, the 3D body poses of surgeons and medical staff can provide important clues for surgical workflow ...

    Vasileios Belagiannis, **nchao Wang in Machine Vision and Applications (2016)

  5. No Access

    Article

    Thoracoscopic repair of congenital diaphragmatic hernia with countermeasures against reported complications for safe outcomes comparable to laparotomy

    Thoracoscopic repair is the preferred treatment for congenital diaphragmatic hernia (CDH); however, several complications, including visceral injury, hypercapnia, and a high incidence of recurrence, have been ...

    Mikihiro Inoue, Keiichi Uchida, Kohei Otake, Yuka Nagano in Surgical Endoscopy (2016)

  6. No Access

    Chapter and Conference Paper

    Extended Co-occurrence HOG with Dense Trajectories for Fine-Grained Activity Recognition

    In this paper we propose a novel feature descriptor Extended Co-occurrence HOG (ECoHOG) and integrate it with dense point trajectories demonstrating its usefulness in fine grained activity recognition. This fe...

    Hirokatsu Kataoka, Kiyoshi Hashimoto, Kenji Iwata in Computer Vision -- ACCV 2014 (2015)

  7. No Access

    Article

    Low NDRG1 mRNA expression predicts a poor prognosis in neuroblastoma patients

    N-myc downstream regulated gene 1 (NDRG1) markedly reduces metastasis of numerous tumors. However, NDRG1’s function in malignant tumors has not been fully determined. Therefore, we investigated the association...

    Kohei Matsushita, Keiichi Uchida, Susumu Saigusa in Pediatric Surgery International (2013)

  8. No Access

    Article

    Self-reported assessment of health-related quality of life in children who underwent restorative proctocolectomy with ileal J-pouch anal anastomosis for ulcerative colitis

    To clarify health-related quality of life (HRQOL) by self-evaluation after restorative proctocolectomy with ileal J-pouch anal anastomosis (IPAA) in children with ulcerative colitis, a questionnaire using the ...

    Keiichi Uchida, Ayumi Kawamata, Kiyoshi Hashimoto in Pediatric Surgery International (2013)

  9. No Access

    Article

    Effect of reduction of slider pitch-mode vibration on magnetic-recording performance at low-clearance head–disk interface

    Aiming at improvements of both stability of slider flying and magnetic-recording performance under a low-clearance condition, a “narrow-grooved slider” was constructed and demonstrated at drive level. The prop...

    Yuki Shimizu, Junguo Xu, Jianhua Li, Hidekazu Kohira in Microsystem Technologies (2012)

  10. No Access

    Article

    Tumor enucleation with preoperative endoscopic transpapillary stenting for pediatric insulinoma

    The 13-year-old boy underwent tumor enucleation for pancreatic head insulinoma close to the pancreatic main duct after a preoperative endoscopic pancreatic stent placed by endoscopic retrograde cholangiopancre...

    Shozo Ide, Keiichi Uchida, Mikihiro Inoue, Yuhki Koike in Pediatric Surgery International (2012)

  11. No Access

    Article

    HsMAD2 mRNA expression may be a predictor of sensitivity to paclitaxel and survival in neuroblastoma

    We investigated the associations between hsMAD2 mRNA expression in tumor cells and sensitivity to paclitaxel or patient prognosis in neuroblastoma.

    Kohei Otake, Keiichi Uchida, Kouji Tanaka, Yuhki Koike in Pediatric Surgery International (2011)

  12. No Access

    Article

    Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45

    It is well known that Fas ligand and anti-Fas antibodies can induce apoptosis, although some cancer cells are resistant to their stimuli. On the other hand, phosphatidylinositol 3’-kinase (PI3 K) and Akt media...

    Mitsuhiko Osaki, Satoru Kase, Keiko Adachi in Journal of Cancer Research and Clinical On… (2004)

  13. No Access

    Article

    Study of fatigue crack nucleation processes by crystalline FE analysis

     In order to accumulate knowledge about how material compositions and manufacturing methods affect fatigue strength, this paper investigates the relationship between the swiftness of the changes in the macrosc...

    Naoki Osawa, Yasumitsu Tomita in Journal of Marine Science and Technology (2003)

  14. Article

    Five familial hypercholesterolemic kindreds in Japan with novel mutations of the LDL receptor gene

    In the course of investigations of familial coronary artery disease in Hokkaido, the northern island of Japan, we identified five families in which multiple members showed elevated plasma levels of low-densit...

    Tsunenori Hirayama, E. Yamaki, Akira Hata, Masahiro Tsuji in Journal of Human Genetics (1998)

  15. No Access

    Article

    A thermally induced meridional cell in rotating fluids

    We study thermally induced meridional circulations of a Boussinesq fluid between two horizontal rotating disks which have axisymmetric temperature distributions and mutually slightly different angular velociti...

    Kiyoshi Hashimoto in Zeitschrift für angewandte Mathematik und Physik ZAMP (1974)