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  1. No Access

    Article

    Promoter methylation levels of microRNA-124 in non-neoplastic rectal mucosa as a potential biomarker for ulcerative colitis-associated colorectal cancer in pediatric-onset patients

    To determine the methylation level of the miR-124 promoter in non-neoplastic rectal mucosa of patients with pediatric-onset ulcerative colitis (UC) to predict UC-associated colorectal cancer (UC-CRC).

    Yuhki Koike, Chengzeng Yin, Yuki Sato, Yuka Nagano, Akira Yamamoto in Surgery Today (2024)

  2. No Access

    Article

    Symptom palliation with QUAD Shot radiation therapy to penile metastasis derived from descending colon cancer: a case report

    A 54-year-old man was diagnosed with descending colon cancer with metastases in the liver, para-aortic lymph nodes, and penis, and chemotherapy was introduced after construction of a colostomy. The patient rep...

    Akira Yamamoto, Hideharu Ieki, Mai Shimamura in International Cancer Conference Journal (2023)

  3. No Access

    Article

    Preoperative myopenia and myosteatosis and their impact on postoperative complications in children with inflammatory bowel disease

    To assess the severity of preoperative myopenia and myosteatosis in pediatric patients with inflammatory bowel disease (IBD) and examine their impact on postoperative complications.

    Mikihiro Inoue, Keiichi Uchida, Yuka Nagano, Kohei Matsushita, Yuhki Koike in Surgery Today (2023)

  4. Article

    Best pre-ductal PaO2 prior to extracorporeal membrane oxygenation as predictor of mortality in patients with congenital diaphragmatic hernia: a retrospective analysis of a Japanese database

    Predicting lethal pulmonary hypoplasia in infants with congenital diaphragmatic hernia (CDH) before extracorporeal membrane oxygenation (ECMO) initiation is difficult. This study aimed to predict lethal pulmon...

    Keita Terui, Taizo Furukawa, Kouji Nagata in Pediatric Surgery International (2021)

  5. Article

    Open Access

    A multilevel dataset of microplastic abundance in the world’s upper ocean and the Laurentian Great Lakes

    A total of 8218 pelagic microplastic samples from the world’s oceans were synthesized to create a dataset composed of raw, calibrated, processed, and gridded data which are made available to the public. The ra...

    Atsuhiko Isobe, Takafumi Azuma, Muhammad Reza Cordova in Microplastics and Nanoplastics (2021)

  6. No Access

    Article

    Optimal timing of delivery for pregnancies with prenatally diagnosed congenital diaphragmatic hernia: a propensity-score analysis using the inverse probability of treatment weighting

    To evaluate the optimal timing of neonates with prenatally diagnosed congenital diaphragmatic hernia (CDH).

    Yoko Kawanishi, Masayuki Endo, Makoto Fujii, Tatsuo Masuda in Journal of Perinatology (2021)

  7. No Access

    Article

    Clinical Discrimination of Chronic Pouchitis After Ileal Pouch-Anal Anastomosis in Patients with Ulcerative Colitis

    We aimed to identify predictive factors for the development of chronic pouchitis after ileal pouch-anal anastomosis in patients with ulcerative colitis.

    Yoshiki Okita, Masaki Ohi, Takahito Kitajima in Journal of Gastrointestinal Surgery (2021)

  8. No Access

    Article

    Optimal timing of surgery in infants with prenatally diagnosed isolated left-sided congenital diaphragmatic hernia: a multicenter, cohort study in Japan

    To date, there is no compelling evidence of the optimal timing of surgery for congenital diaphragmatic hernia (CDH). This study aimed to establish the optimal timing of surgery in neonates with isolated left-s...

    Masaya Yamoto, Satoko Ohfuji, Naoto Urushihara, Keita Terui, Kouji Nagata in Surgery Today (2021)

  9. No Access

    Article

    Prognosis of conventional vs. high-frequency ventilation for congenital diaphragmatic hernia: a retrospective cohort study

    To determine the appropriate initial ventilatory mode for neonatal congenital diaphragmatic hernia (CDH) by comparing patient prognosis following conventional mechanical ventilation (CMV) versus high-frequency...

    Makiko Fuyuki, Noriaki Usui, Tomoaki Taguchi, Masahiro Hayakawa in Journal of Perinatology (2021)

  10. Article

    Open Access

    Novel TNFAIP3 microdeletion in a girl with infantile-onset inflammatory bowel disease complicated by a severe perianal lesion

    A20 haploinsufficiency (HA20), a disease caused by loss-of-function TNFAIP3 mutations, manifests various autoinflammatory and/or autoimmune symptoms. Some cases of HA20 were initially diagnosed as very early onse...

    Kosuke Taniguchi, Mikihiro Inoue, Katsuhiro Arai, Keiichi Uchida in Human Genome Variation (2021)

  11. Article

    Open Access

    Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation

    Necrotizing enterocolitis (NEC) is a devastating disease of premature infants with high mortality rate, indicating the need for precision treatment. NEC is characterized by intestinal inflammation and ischemia...

    Yuhki Koike, Bo Li, Niloofar Ganji, Haitao Zhu, Hiromu Miyake in Nature Communications (2020)

  12. Article

    Open Access

    Possible fluid discharge associated with faults observed by a high-resolution dense-2D seismic reflection survey in Uchiura Bay off Numazu, Japan

    Although fluid behavior along faults has often been associated with earthquakes and hydrocarbon accumulation, few observations of active, ongoing fluid discharge along the faults exist. We conducted a dense-2D...

    Tetsuro Tsuru, **-Oh Park, Kazuo Amakasu, Tetsuo No in Earth, Planets and Space (2020)

  13. Article

    Open Access

    The relationship between preoperative T helper cytokines in the ileal mucosa and the pathogenesis of pouchitis

    Although the etiology of pouchitis remains unknown, inflammatory cytokines are significantly associated with the pathogenesis of pouchitis. The cytokine responses that characterize inflammatory bowel diseases ...

    Takahito Kitajima, Yoshiki Okita, Mikio Kawamura, Satoru Kondo in BMC Gastroenterology (2020)

  14. No Access

    Article

    Risk factors for pneumothorax associated with isolated congenital diaphragmatic hernia: results of a Japanese multicenter study

    This study aimed to elucidate the clinical characteristics of neonates with congenital diaphragmatic hernia (CDH) associated with pneumothorax and evaluate the risk factors for the development of pneumothorax.

    Kazunori Masahata, Noriaki Usui, Kouji Nagata in Pediatric Surgery International (2020)

  15. No Access

    Article

    Occurrence of a temperate coastal flatfish, the marbled flounder Pseudopleuronectes yokohamae, at high water temperatures in a shallow bay in summer detected by acoustic telemetry

    The marbled flounder Pseudopleuronectes yokohamae, a flatfish found in temperate coastal waters, is an important commercial species in the northwestern Pacific Ocean, but little is known of its distribution and m...

    Hiromichi Mitamura, Nobuaki Arai, Masakazu Hori, Keiichi Uchida in Fisheries Science (2020)

  16. Article

    Open Access

    Abundance of non-conservative microplastics in the upper ocean from 1957 to 2066

    Laboratory-based studies have suggested that marine organisms can be harmed by ingesting microplastics. However, unless the current and future microplastic abundance in the ocean environment is quantified, the...

    Atsuhiko Isobe, Shinsuke Iwasaki, Keiichi Uchida, Tadashi Tokai in Nature Communications (2019)

  17. No Access

    Chapter and Conference Paper

    Influence of Behavioral Patterns of Several Fish Species on Their Radioactive Cesium Concentrations Revealed with a Biotelemetry System After the Nuclear Accident Caused by the 2011 Great East Japan Earthquake

    The Great East Japan Earthquake and subsequent tsunami on March 2011 damaged Fukushima Daiichi Nuclear Power Plant (FDNPP), and a part of radioactive materials released from FDNPP entered in coastal waters of ...

    Keiichi Uchida, Kohei Hasegawa in Oceanography Challenges to Future Earth (2019)

  18. No Access

    Chapter

    Enterocolitis

    Hirschsprung’s disease-associated enterocolitis is the most common complication of Hirschsprung’s disease. Clinical symptoms of Hirschsprung’s disease-associated enterocolitis vary from mild to severe, and it ...

    Keiichi Uchida, Mikihiro Inoue, Yuhki Koike in Hirschsprung’s Disease and the Allied Diso… (2019)

  19. No Access

    Article

    Contaminated or dirty wound operations and methicillin-resistant Staphylococcus aureus (MRSA) colonization during hospitalization may be risk factors for surgical site infection in neonatal surgical patients

    Establishment of evidence-based best practices for preventing surgical site infection (SSI) in neonates is needed. SSI in neonates, especially those with a low birth weight, is potentially life-threatening. We...

    Mikihiro Inoue, Keiichi Uchida, Takashi Ichikawa in Pediatric Surgery International (2018)

  20. No Access

    Article

    Impact of relationship between the stoma site and the primary incision on occurrence of laparotomy wound infection in contaminated or dirty wound operations in neonates

    In neonatal surgical patients requiring an enterostomy, there is no definitive recommendation regarding the ideal enterostomy location: at the edge of the primary incision or at a different incision.

    Mikihiro Inoue, Keiichi Uchida, Yuka Nagano in Pediatric Surgery International (2018)

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