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  1. No Access

    Article

    Comparison of the impact of two post-remission therapy regimens on cardiac events in acute myeloid leukemia patients undergoing allogeneic hematopoietic stem cell transplantation

    High-dose cytarabine (HD-AraC) or anthracycline-containing chemotherapies are used as post-remission therapy for acute myeloid leukemia (AML) patients. However, it remains unclear which regimen would be better...

    ** Hayakawa, Hideki Nakasone, Daisuke Minakata… in International Journal of Hematology (2022)

  2. No Access

    Article

    Chronic liver graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients during tapering or after stop** calcineurin inhibitors

    Chronic graft-versus-host disease (cGVHD) of the liver is often observed in allogeneic hematopoietic stem cell transplantation (allo-HSCT) during tapering or after stop** calcineurin inhibitors (CI). We cond...

    Kazuki Yoshimura, Shun-ichi Kimura… in International Journal of Hematology (2021)

  3. Article

    Open Access

    Features of repertoire diversity and gene expression in human cytotoxic T cells following allogeneic hematopoietic cell transplantation

    Cytomegalovirus reactivation is still a critical concern following allogeneic hematopoietic cell transplantation, and cellular immune reconstitution of cytomegalovirus-specific cytotoxic T-cells is necessary f...

    Hideki Nakasone, Machiko Kusuda, Kiriko Terasako-Saito… in Communications Biology (2021)

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  4. No Access

    Article

    Negative impact of chronic graft-versus-host disease and glucocorticoid on the recovery of physical function after allogeneic hematopoietic stem cell transplantation

    Quality of life of patients who undergo allogeneic hematopoietic stem cell transplantation (HSCT) temporally deteriorates and recovers over several years. We retrospectively evaluate the impact of chronic graf...

    ** Hayakawa, Daijiro Miyamura, Shun-ichi Kimura… in Bone Marrow Transplantation (2019)

  5. No Access

    Article

    Associations between febrile neutropenia-related parameters and the risk of acute GVHD or non-relapse mortality after allogeneic hematopoietic stem cell transplantation

    Infection and inflammation can induce acute graft-vs.-host disease (aGVHD). We hypothesized that febrile neutropenia early after allogeneic hematopoietic cell transplantation (HCT) would increase the risk of a...

    Kazuaki Kameda, Shun-ichi Kimura, Yukiko Misaki… in Bone Marrow Transplantation (2019)

  6. No Access

    Article

    Outcome of gastrointestinal graft-versus-host disease according to the treatment response

    The optimal treatment strategy for gastrointestinal graft-versus-host disease (GI-GVHD) after allogeneic hematopoietic cell transplantation remains to be established. We retrospectively analyzed 68 cases of GI...

    Masaharu Tamaki, Hideki Nakasone, Yukiko Misaki, Kazuki Yoshimura… in Annals of Hematology (2018)

  7. No Access

    Article

    Lower glomerular filtration rate predicts increased hepatic and mucosal toxicity in myeloma patients treated with high-dose melphalan

    High-dose melphalan followed by autologous hematopoietic stem cell transplantation (ASCT) is a standard treatment for younger myeloma patients. However, the correlation between its toxicity and renal impairmen...

    Masaharu Tamaki, Hideki Nakasone, Ayumi Gomyo… in International Journal of Hematology (2018)

  8. No Access

    Article

    Pseudo-autologous stem cell transplantation for donor-derived mantle cell lymphoma 12 years after allogeneic transplantation

    Donor-derived malignancy is a rare morbidity after allogeneic hematopoietic stem cell transplantation (HSCT), in which most previous cases have presented as acute leukemia or myelodysplastic syndrome. There ha...

    Masaharu Tamaki, Hidenori Wada, Ayumi Gomyo… in International Journal of Hematology (2018)

  9. No Access

    Article

    Safety of avoiding systemic corticosteroid administration for grade II acute graft-versus-host disease limited to the skin

    We hypothesized that systemic corticosteroid administration would be safely avoided not only in grade I acute graft-versus-host disease (GVHD) but also in selected patients with grade II acute GVHD limited to ...

    Kazuaki Kameda, Shinichi Kako, ** Hayakawa, Yu Akahoshi… in Annals of Hematology (2018)

  10. No Access

    Article

    Comparison of levofloxacin and garenoxacin for antibacterial prophylaxis during neutropenia

    Levofloxacin (LVFX) is widely used for antibacterial prophylaxis during neutropenia. Garenoxacin (GRNX), which has been investigated in Japan, has stronger antibacterial activity than LVFX against gram-positiv...

    Ryoko Yamasaki, Junya Kanda, Yu Akahoshi… in International Journal of Hematology (2017)

  11. No Access

    Article

    Meta-analysis of treatment with rabbit and horse antithymocyte globulin for aplastic anemia

    Aplastic anemia patients who received rabbit antithymocyte globulin exhibited response and survival rates inferior to those who received horse antithymocyte globulin in several studies. Therefore, we conducted...

    ** Hayakawa, Junya Kanda, Yu Akahoshi… in International Journal of Hematology (2017)

  12. No Access

    Article

    Assessment of the ovarian reserve with anti-Müllerian hormone in women who underwent allogeneic hematopoietic stem cell transplantation using reduced-intensity conditioning regimens or myeloablative regimens with ovarian shielding

    Conditioning regimens that include cyclophosphamide (CY) and total body irradiation (TBI) induce severe gonadal toxicity and permanent infertility in approximately 90 % of female patients who undergo hematopoi...

    Hirofumi Nakano, Masahiro Ashizawa, Yu Akahoshi… in International Journal of Hematology (2016)

  13. No Access

    Article

    Meta-analysis and meta-regression analysis to compare the outcomes of chemotherapy for T- and B-lineage acute lymphoblastic leukemia (ALL): the use of dexamethasone, l-asparaginase, and/or methotrexate may improve the outcome of T-lineage ALL

    The effects of intensive regimens and the roles of drugs used might differ between T- and B-lineage acute lymphoblastic leukemia (ALL). We performed a literature search for clinical studies published from Janu...

    Shinichi Kako, Yu Akahoshi, Naonori Harada, Hirofumi Nakano… in Annals of Hematology (2016)

  14. No Access

    Article

    Low-dose acyclovir prophylaxis for the prevention of herpes simplex virus and varicella zoster virus diseases after autologous hematopoietic stem cell transplantation

    Limited data are available on prophylaxis for herpes simplex virus (HSV) and varicella zoster virus (VZV) disease following autologous hematopoietic stem cell transplantation (auto-HCT). We retrospectively rev...

    Koji Kawamura, ** Hayakawa, Yu Akahoshi… in International Journal of Hematology (2015)

  15. No Access

    Article

    Pharmacokinetics study of once-daily intravenous busulfan in conditioning regimens for hematopoietic stem cell transplantation

    In Japan, intravenous busulfan (ivBu) is usually given four times per day as an infusion at 0.8 mg/kg over 2 h. However, as this requires a midnight administration, a once-daily infusion of ivBu at 3.2 mg/kg o...

    Miki Sato, Shinichi Kako, Kana Matsumoto… in International Journal of Hematology (2015)

  16. No Access

    Article

    Severe oral infection due to Lactobacillus rhamnosus during induction chemotherapy for acute myeloid leukemia

    We report a case of severe oral infection with a high fever due to Lactobacillus rhamnosus during induction chemotherapy for acute myeloid leukemia. The patient did not improve on treatment with meropenem, clinda...

    Yuko Ishihara, Junya Kanda, Kaori Tanaka… in International Journal of Hematology (2014)

  17. No Access

    Article

    Protection of ovarian function by two distinct methods of ovarian shielding for young female patients who receive total body irradiation

    To prevent ovarian dysfunction due to total body irradiation, we started ovarian shielding at our center (Saitama Medical Center, Jichi Medical University (SMC-JMU)) with a long source axis distance, which is ...

    Yoshinobu Kanda, Hidenori Wada, Ryoko Yamasaki, Koji Kawamura… in Annals of Hematology (2014)