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    Article

    An economically advantageous amorphous solid dispersion of the fixed combination of lopinavir and ritonavir

    Solid dispersion strategies have recently been used to increase the solubility and bioavailability of poorly soluble drugs. Among these various strategies for solid dispersion, the method using polymers and ad...

    Taek-Seon Yun, Minwoo Jung, Ki-Hyun Bang in Journal of Pharmaceutical Investigation (2023)

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    Effect of surfactant on the preparation and characterization of gemcitabine-loaded particles

    Gemcitabine is used in the treatment of several solid tumors as one of anticancer nucleoside analogues and is necessary to administer high doses to achieve the desired therapeutic response. However, this treat...

    Ji-Ho Lim, Young-Guk Na, Hong-Ki Lee in Journal of Pharmaceutical Investigation (2019)

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    Article

    Improvement of cellular uptake of hydrophilic molecule, calcein, formulated by liposome

    The aim of this study was to prepare the liposome with 1,2-distearoyl-sn-glycero-3-phosphocholine, 1.2 dioleoyl-sn-glycero-3-phosphoethanolamine, cholesteyl hemisuccinate, calcein as a drug model and evaluate ...

    Su-Min Han, Young-Guk Na, Han-Sol Lee, Gi-Ho Son in Journal of Pharmaceutical Investigation (2018)