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  1. Article

    Open Access

    Response surface methodology mediated optimization of phytosulfokine and plant growth regulators for enhanced protoplast division, callus induction, and somatic embryogenesis in Angelica Gigas Nakai

    Angelica Gigas (Purple parsnip) is an important medicinal plant that is cultivated and utilized in Korea, Japan, and China. It contains bioactive substances especially coumarins with anti-inflammatory, anti-plate...

    Han-Sol Lee, Jong-Eun Han, Eun-Kyung Bae, Eun Yee Jie, Suk Weon Kim in BMC Plant Biology (2024)

  2. No Access

    Article

    Isolation, culture of protoplasts of Angelica gigas Nakai and regeneration of plants via somatic embryogenesis

    In plant biotechnology, protoplasts are a versatile tool since they are very helpful for both fundamental biology studies and for genetic improvement and genome editing studies. In many plant species, however,...

    Han-Sol Lee, Jong-Eun Han, Eun Yee Jie in Plant Cell, Tissue and Organ Culture (PCTO… (2023)

  3. Article

    Open Access

    The landscape of US elementary mathematics teacher education: course requirements for mathematics content and methods

    The adequate preparation of future teachers of mathematics is critical, requiring sufficient opportunities to develop both pedagogical skill and content knowledge. Yet, despite new recommendations for mathemat...

    Brette Garner, Jen Munson, Gladys Krause in Journal of Mathematics Teacher Education (2023)

  4. No Access

    Article

    Suspension culture of somatic embryos for the production of high-value secondary metabolites

    Secondary metabolites from plants are ubiquitous and have applications in medicines, food additives, scents, colorants, and natural pesticides. Biotechnological production of secondary metabolites that have ec...

    Hosakatte Niranjana Murthy in Physiology and Molecular Biology of Plants (2023)

  5. Article

    Open Access

    In vitro infection efficiency of nervous necrosis virus alters depending on amount of viral particles adsorbed onto cells

    Nervous necrosis virus (NNV) in the family Nodaviridae is one of the simplest spherical RNA viruses and is pathogenic to many fish species. We investigated the effect of purified NNV on striped snakehead cells (S...

    Han Sol Lee, Hyun Jung Gye, Toyohiko Nishizawa in Scientific Reports (2023)

  6. No Access

    Article

    Updated Minimum Weighted Norm Based Electromagnetic Field Control for a Magnetically Actuated Microrobot

    Herein, we present a novel electromagnetic field control methodology against a heating problem that can perform both desired actuation and lower heating of an electromagnet actuator comprising several electrom...

    Jayoung Kim, Han-Sol Lee, Cheong Lee in International Journal of Control, Automati… (2023)

  7. Article

    Open Access

    Development of simultaneous analytical method for the determination of fluazaindolizine and its seven metabolites in agricultural products by liquid chromatography tandem mass spectrometry

    A simultaneous analytical method has been developed for quantification and confirmation of the nematicide fluazaindolizine and its seven metabolites (IN-A5760, IN-F4106, IN-QEK31, IN-QZY47, IN-TMQ01, IN-UNS90 ...

    Su Jung Lee, Han Sol Lee, Sun Young Gu, Hye-Sun Shin in Applied Biological Chemistry (2022)

  8. No Access

    Article

    High-density neural recording system design

    Implantable medical devices capable of monitoring hundreds to thousands of electrodes have received great attention in biomedical applications for understanding of the brain function and to treat brain disease...

    Han-Sol Lee, Kyeongho Eom, Minju Park, Seung-Beom Ku in Biomedical Engineering Letters (2022)

  9. Article

    Open Access

    Synaptic plasticity-dependent competition rule influences memory formation

    Memory is supported by a specific collection of neurons distributed in broad brain areas, an engram. Despite recent advances in identifying an engram, how the engram is created during memory formation remains ...

    Yire Jeong, Hye-Yeon Cho, Mujun Kim, Jung-Pyo Oh, Min Soo Kang in Nature Communications (2021)

  10. No Access

    Article

    An overview of chondrosarcoma with a focus on nanoscale therapeutics

    Chondrosarcoma (CHS) is the second most common sarcoma. However, pathogenesis and etiology of this malignant tumor are still unclear. The primary treatment method for CHS is surgery, and CHS is often resistant...

    Dong Hyun Kim, Han Sol Lee, Yong-Hyeon Mun in Journal of Pharmaceutical Investigation (2020)

  11. Article

    Open Access

    Simultaneous determination of the metabolites of the herbicide metazachlor in agricultural crops by LC–MS/MS

    To manage the safety of the herbicide metazachlor, analytical methods are required for the determination of metazachlor metabolites in agricultural crops. Herein, a liquid chromatography–tandem mass spectromet...

    Ji-Su Park, Han Sol Lee, Sung Min Cho, Su Jung Lee in Applied Biological Chemistry (2020)

  12. No Access

    Article

    Stability evaluation of H3N2 influenza split vaccine in drying process for solidification

    Currently, most vaccines have been manufactured in liquid forms that are needed a cold-chain system. However, this system does not guarantee the stability of vaccines always and requires a high cost. Although ...

    Sung-** Kim, Young-Guk Na, Hong-Ki Lee in Journal of Pharmaceutical Investigation (2020)

  13. No Access

    Article

    Medical Microrobot - Wireless Manipulation of a Drug Delivery Carrier through an External Ultrasonic Actuation: Preliminary Results

    To achieve precise and untethered clinical therapeutics, microrobots have been widely researched. However, because conventional microrobot actuation is based on magnetic forces generated by a magnetic field an...

    Han-Sol Lee, Gwangjun Go, Eunpyo Choi in International Journal of Control, Automati… (2020)

  14. No Access

    Article

    Single enzyme nanoparticle, an effective tool for enzyme replacement therapy

    The term “single enzyme nanoparticle” (SEN) refers to a chemically or biologically engineered single enzyme molecule. SENs are distinguished from conventional protein nanoparticles in that they can maintain th...

    Dong Hyun Kim, Han Sol Lee, Tae-Wan Kwon, Young-Min Han in Archives of Pharmacal Research (2020)

  15. No Access

    Article

    Crystal Phase Control of ε-Ga2O3 Fabricated using by Metal-Organic Chemical Vapor Deposition

    ε-Ga2O3 thin films were grown on (0001) sapphire, (0001) GaN, and a low-temperature buffer layer at different temperatures and flow rates of bubbled H2O (oxygen source) using trimethylgallium and H2O as precursor...

    Sang Hun Park, Han Sol Lee, Hyung Soo Ahn in Journal of the Korean Physical Society (2019)

  16. No Access

    Article

    Improvement of cellular uptake of hydrophilic molecule, calcein, formulated by liposome

    The aim of this study was to prepare the liposome with 1,2-distearoyl-sn-glycero-3-phosphocholine, 1.2 dioleoyl-sn-glycero-3-phosphoethanolamine, cholesteyl hemisuccinate, calcein as a drug model and evaluate ...

    Su-Min Han, Young-Guk Na, Han-Sol Lee, Gi-Ho Son in Journal of Pharmaceutical Investigation (2018)

  17. Article

    Open Access

    Anterior cingulate cortex and its input to the basolateral amygdala control innate fear response

    Prefrontal brain areas are implicated in the control of fear behavior. However, how prefrontal circuits control fear response to innate threat is poorly understood. Here, we show that the anterior cingulate co...

    **ho Jhang, Hyoeun Lee, Min Soo Kang, Han-Sol Lee, Hyungju Park in Nature Communications (2018)

  18. No Access

    Article

    Decline patterns and risk assessment of 10 multi-class pesticides in young sprout amaranth (Amaranthus mangostanus) under greenhouse growing conditions

    The present study was designed to investigate the residual decline pattern and the risk assessment of 10 different class pesticides, namely azoxystrobin, boscalid, diazinon, diethofencarb, difenoconazole, etof...

    In Kyung Kim, Sung-Woo Kim, A. M. Abd El-Aty in Environmental Science and Pollution Resear… (2017)

  19. No Access

    Article

    Dissipation kinetics, pre-harvest residue limits, and hazard quotient assessments of pesticides flubendiamide and fluopicolide in Korean melon (Cucumis melo L. var. makuwa) grown under regulated conditions in plastic greenhouses

    The dissipation kinetics, pre-harvest residue limits, and hazard quotient (HQ) assessments of the pesticides flubendiamide and fluopicolide were conducted for Korean melon (Cucumis melo L. var. makuwa) cultivated...

    Md. Humayun Kabir, A. M. Abd El-Aty in Environmental Science and Pollution Resear… (2017)

  20. No Access

    Article

    Residue analysis of picoxystrobin in oriental melon using gas chromatography coupled with electron capture detection and mass spectrometric confirmation: application to dissipation kinetics and risk assessment

    This study was carried out to determine the residual amounts of picoxystrobin in oriental melon (Cucumis melo L.) grown under plastic house conditions at two different sites. Samples collected over 10 days were e...

    Md. Humayun Kabir, Md. Musfiqur Rahman, A. M. Abd El-Aty in Food Science and Biotechnology (2017)

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