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Article
Psychometric utility of the international HIV dementia scale and Montreal Cognitive Assessment in HIV-associated asymptomatic neurocognitive impairment
There is a growing need for brief screening measures for HIV Associated Neurocognitive Disorders (HAND). We compared two commonly used measures (the Montreal Cognitive Assessment [MoCA] and the International H...
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Article
Assessment, prevalence, and correlates of frailty among middle-aged adults with HIV in rural Uganda
We investigated the prevalence and risk factors for frailty among people with HIV (PWH) in rural Uganda (n = 55, 47% male, mean age 44 years). Frailty was defined according to the Fried criteria with self-reporte...
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Chapter
Neurocognitive Complications of HIV Infection in Low-Income Countries
There is a paucity of information on neurocognitive dysfunction in individuals with HIV in resource-limited regions, despite the fact that these areas have the greatest burden of infection. HIV-associated neur...
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Article
Open AccessPrescribed fire science: the case for a refined research agenda
The realm of wildland fire science encompasses both wild and prescribed fires. Most of the research in the broader field has focused on wildfires, however, despite the prevalence of prescribed fires and demons...
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Article
Limited correlation between systemic biomarkers and neurocognitive performance before and during HIV treatment
The AIDS Clinical Trials Group (ACTG) study A5303 investigated the associations between neuropsychological performance (NP) and inflammatory biomarkers in HIV-infected participants. Fifteen NP tests were admin...
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Article
Heterogeneity in neurocognitive change trajectories among people with HIV starting antiretroviral therapy in Rakai, Uganda
Considerable heterogeneity exists in patterns of neurocognitive change in people with HIV (PWH). We examined heterogeneity in neurocognitive change trajectories from HIV diagnosis to 1–2 years post-antiretrovi...
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Article
Open AccessSimilar neurocognitive outcomes after 48 weeks in HIV-1-infected participants randomized to continue tenofovir/emtricitabine + atazanavir/ritonavir or simplify to abacavir/lamivudine + atazanavir
Human immunodeficiency virus (HIV)-associated neurocognitive disorders can persist in many patients despite achieving viral suppression while on antiretroviral therapy (ART). Neurocognitive function over 48 we...
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Article
Open AccessAuthor Correction: Identifying long-term stable refugia for relict plant species in East Asia
In the original version of this Article, an incorrect sample size was provided for the number of relict species (443 instead of 442) and the number of relict forests (423 instead of 422). These errors have bee...
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Article
Open AccessIdentifying long-term stable refugia for relict plant species in East Asia
Today East Asia harbors many “relict” plant species whose ranges were much larger during the Paleogene-Neogene and earlier. The ecological and climatic conditions suitable for these relict species have not bee...
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Reference Work Entry In depth
Global NeuroAIDS
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Reference Work Entry In depth
Neurotoxic Consequences of Antiretroviral Therapies
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Article
Cerebrospinal fluid biomarkers and HIV-associated neurocognitive disorders in HIV-infected individuals in Rakai, Uganda
In the USA, increased cerebrospinal fluid (CSF) inflammatory cytokines have been observed in antiretroviral therapy (ART)-naive, HIV-seropositive individuals with HIV-associated neurocognitive disorder (HAND)....
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Living Reference Work Entry In depth
Global NeuroAIDS
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Article
HIV subtype is not associated with dementia among individuals with moderate and advanced immunosuppression in Kampala, Uganda
HIV-associated neurocognitive disorders (HAND) are a common neurological manifestation of HIV infection. A previous study suggested that HIV dementia may be more common among patients with subtype D virus than...
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Article
Longitudinal Characterization of Depression and Mood States Beginning in Primary HIV Infection
Though depression is known to frequently afflict those with chronic HIV, mood during the early course of HIV is not well characterized. In a prospective study we assessed mood during primary HIV infection [pri...
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Living Reference Work Entry In depth
Neurotoxic Consequences of Antiretroviral Therapies
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Article
Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy
Emerging evidence suggests that CNS injury and neurocognitive impairment persist in the setting of chronic HIV infection and combination antiretroviral therapy (CART). Yet, whether neurological injury can prog...
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Article
Longitudinal neuropsychological test performance among HIV seropositive individuals in Uganda
This study was conducted to evaluate longitudinal neuropsychological testing performance over a 12-month period among HIV + individuals, and to evaluate the impact of antiretroviral therapy (ART) initiation on...
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Article
Global NeuroAIDS Roundtable
In May 2012, the Division of AIDS Research at the National Institute of Mental Health (NIMH) organized the “Global NeuroAIDS Roundtable” in conjunction with the 11th International Symposium on Neurovirology an...
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Article
Antiretroviral neurotoxicity
Combination antiretroviral therapy (CART) has proven to effectively suppress systemic HIV burden, however, poor penetration into the central nervous system (CNS) provides incomplete protection. Although the se...
