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    cGAS drives noncanonical-inflammasome activation in age-related macular degeneration

    Degeneration of the retinal pigment epithelium is a hallmark of geographic atrophy, a type of age-related macular degeneration. Kerur et al. show that this degeneration results from a multistep pathway in which m...

    Nagaraj Kerur, Shinichi Fukuda, Daipayan Banerjee, Younghee Kim… in Nature Medicine (2018)