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Article
Open AccessAngiotensin II increases gene expression after selective intra-arterial adenovirus delivery in a rabbit model assessed using in vivo SSTR2-based reporter imaging
Gene therapy has been hampered by low expression upon in vivo delivery. Using a somatostatin receptor type 2 (SSTR2)-based reporter, we assessed whether angiotensin II (AII) can improve gene expression by aden...
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Article
Development of Multi-Membrane Near-Infrared Diode Mass Spectrometer for Field Analysis of Aromatic Hydrocarbons
Membrane Inlet Mass Spectrometry (MIMS) is a technique that incorporates a semi-permeable membrane selective for differing organic molecules and chemistries. This eliminates the need for time-consuming sample ...
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Article
Hepatic Arterial Embolization with Doxorubicin-Loaded Superabsorbent Polymer Microspheres in a Rabbit Liver Tumor Model
The pharmacokinetic profile after hepatic arterial embolization with superabsorbent microspheres (QuadraSpheres) loaded with doxorubicin was studied.
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Article
Pure Ethiodized Oil-based Transcatheter Ablative Therapy in Normal Rabbit Kidneys and Kidneys Inoculated with VX-2 Carcinoma
To evaluate the efficacy of ablation with selective arterial injection of pure ethiodized oil followed by arterial occlusion with 9:1 ethanol–Ethiodol mixture (EEM) and coil placement in normal rabbit kidneys ...
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Chapter
Imaging of Angiogenesis
Angiogenesis is the process by which new vessels grow toward and into a tissue. It is required for several physiological processes including embryogenesis, corpus luteum formation, and wound healing. It is als...
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Article
Formation and Characterization of Cisplatin-Loaded Poly(benzyl 1-glutamate) Microspheres for Chemoembolization
Chemoembolization using microspheres of 100- to 200-µm is a useful way to treat primary and secondary hepatic tumors. In a search for a better embolic material, we described in detail the preparation and chara...
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Article
Monodisk: Device for percutaneous transcatheter closure of cardiac septal defects
The Monodisk, a device to facilitate percutaneous closure of cardiac septal defects, was developed and testedin vitro andin vivo. Atrial septal defects (8–10 mm) were created in five dogs using transcatheter tech...
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Article
Treatment of experimentally induced atherosclerosis in swine iliac arteries: A comparison of self-expanding and balloon-expanded stents
Atherosclerosis was induced in 20 Hanford miniature swine. Subsequently, one iliac artery lesion in each of 16 pigs was stented with either a self-expanding (8 pigs) or a balloon-expanded (8 pigs) stent. Immed...
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Article
Synthesis and in Vitro Receptor Binding Studies of Fluorotamoxifen Analogues
We describe the synthesis of new fluorotamoxifen analogues with the fluorine atom positioned on the end of the aliphatic chain of tamoxifen. The binding of fluorotamoxifens to cytosol estrogen receptors of rat...
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Chapter
Potential Breast Tumor Imaging Agents: Fluorotamoxifen and Derivatives
This study is aimed at develo** a ligand to be used for imaging estrogen receptor positive breast tumors by Positron Emission Tomography (PET). We describe the synthesis of fluorotamoxifen analogs with the f...