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  1. No Access

    Article

    Pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia treated with arsenic trioxide

    To investigate the pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia (APL) treated with arsenic trioxide (ATO) at a daily dose of 0.15 mg/kg.

    Shinya Fujisawa, Ryuzo Ohno, Kazuyuki Shigeno… in Cancer Chemotherapy and Pharmacology (2007)

  2. No Access

    Article

    Diagnostic and prognostic usefulness of N 1,N 8-diacetylspermidine and N 1,N 12-diacetylspermine in urine as novel markers of malignancy

    Recently, we found N 1,N 8-diacetylspermidine (Ac2Spd) and N 1,N 12-diacetylspermine (Ac2Spm) in human urine, and noted that their amount increased significantly in patients with urogenital malignancies. Previou...

    Kyoko Hiramatsu, Masayuki Sugimoto… in Journal of Cancer Research and Clinical On… (1997)

  3. No Access

    Article

    Significance of urinaryN 1,N 8-diacetylspermidine andN 1,N 12-diacetylspermine as indicators of neoplastic diseases

    N 1,N 8-Diacetylspermidine (Ac2Spd) andN 1,N 12 diacetylspermine (Ac2Spm), the occurrence of which in healthy human urine was demonstrated recently, increased much more frequently and markedly than total polyami...

    Masayuki Sugimoto, Kyoko Hiramatsu… in Journal of Cancer Research and Clinical On… (1995)