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  1. Article

    Open Access

    Multimodal single-cell analyses of peripheral blood mononuclear cells of COVID-19 patients in Japan

    SARS-CoV-2 continues to spread worldwide. Patients with COVID-19 show distinct clinical symptoms. Although many studies have reported various causes for the diversity of symptoms, the underlying mechanisms are...

    Yukie Kashima, Taketoshi Mizutani, Kaori Nakayama-Hosoya in Scientific Reports (2023)

  2. Article

    Open Access

    Programmed cell death ligand 1 measurement study in granulocyte colony-stimulating factor-producing lung cancer: an observational study

    Granulocyte colony-stimulating factor (G-CSF)-producing lung cancer induces severe inflammation and a high white blood cell (WBC) count and is associated with poor prognosis. A recent case of G-CSF-producing l...

    Kazuhito Miyazaki, Aya Shiba, Toshiki Ikeda, Yuko Higashi, Masaharu Aga in BMC Cancer (2022)

  3. Article

    Open Access

    Acute pancreatitis or severe increase in pancreatic enzyme levels following remdesivir administration in COVID-19 patients: an observational study

    Remdesivir has been shown to reduce recovery time and mortality among patients with coronavirus disease 2019 (COVID-19). However, data regarding the efficacy and safety of remdesivir use are limited in Japan. ...

    Kazuhito Miyazaki, Yukihiro Yoshimura, Nobuyuki Miyata in Scientific Reports (2022)

  4. Article

    Open Access

    Examination of endobronchial ultrasound-guided transbronchial needle aspiration using a puncture needle with a side trap

    Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is useful for diagnosing hilar and mediastinal lymph node enlargement; however, specimens obtained are often small and inadequate fo...

    Kazuhito Miyazaki, Yuya Hirasawa, Masaharu Aga, Naoto Aiko in Scientific Reports (2021)

  5. Article

    Open Access

    Comparison of the efficacies of first-generation epidermal growth factor receptor tyrosine kinase inhibitors for brain metastasis in patients with advanced non-small-cell lung cancer harboring EGFR mutations

    Compared with standard chemotherapy, epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are more effective in patients with advanced non-small-cell lung cancer (NSCLC) harboring EGFR mutat...

    Naoto Aiko, Tsuneo Shimokawa, Kazuhito Miyazaki, Yuki Misumi, Yoko Agemi in BMC Cancer (2018)