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Article
HIV-1 persistence in CD4+ T cells with stem cell–like properties
Understanding how and where HIV-1 infection persists in the body is crucial for efforts to eradicate the viral reservoir. Now Mathias Lichterfeld and his colleagues report that HIV-1 can infect CD4+ T memory stem...
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Article
Open AccessSystemic inhibition of myeloid dendritic cells by circulating HLA class I molecules in HIV-1 infection
HIV-1 infection is associated with profound dysfunction of myeloid dendritic cells, for reasons that remain ill-defined. Soluble HLA class I molecules can have important inhibitory effects on T cells and NK ce...