3 Result(s)
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Katarzyna Chojnowska
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Article
Open AccessLoss of Y in regulatory T lymphocytes in the tumor micro-environment of primary colorectal cancers and liver metastases
Male sex is a risk factor for colorectal cancer (CRC) with higher illness burden and earlier onset. Thus, we hypothesized that loss of chromosome Y (LOY) in the tumor micro-environment (TME) might be involved ...
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Article
Open AccessSize matters: the impact of nucleus size on results from spatial transcriptomics
Visium Spatial Gene Expression (ST) is a method combining histological spatial information with transcriptomics profiles directly from tissue sections. The use of spatial information has made it possible to di...
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Article
Open AccessPersonalized health risk assessment based on single-cell RNA sequencing analysis of a male with 45, X/48, XYYY karyotype
Numeric sex chromosome abnormalities are commonly associated with an increased cancer risk. Here, we report a 14-year-old boy with a rare mosaic 45, X/48, XYYY karyotype presenting with subtle dysmorphic featu...
