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  1. No Access

    Article

    Efficient Synthesis and Biological Evaluation of Topopyrone C Derivatives

    A concise route to the synthesis of topopyrone C derivatives is reported. The 1,4-dihydroxyanthraquinone was converted to the target compound 2 using five-step sequences, while only three steps were required to a...

    Shahid Aziz, Habib-ur-Rehman, Muhammad Aziz Ch… in Chemistry of Natural Compounds (2016)

  2. No Access

    Article

    Antimicrobial activity of two mellein derivatives isolated from an endophytic fungus

    Phytochemical investigations of the endophytic fungus of an unidentified Ascomycete, isolated from Meliotus dentatus led to the isolation of two new polyketide metabolites named cis-4-acetoxyoxymellein and 8-deox...

    Hidayat Hussain, Farah Jabeen, Karsten Krohn… in Medicinal Chemistry Research (2015)

  3. No Access

    Chapter

    Antifungal Metabolites of Endophytic Fungi

    Not only medicinal plants, but also the endophytic fungi that colonize them are excellent sources of antifungal metabolites. In some cases, the substances detected in plants have been shown to be secondary met...

    Karsten Krohn, Barbara Schulz in Antifungal Metabolites from Plants (2013)

  4. No Access

    Article

    Antiplasmodial activity of compounds from Drypetes gerrardii

    Margaret Mwihaki Ng′ang′a, Hidayat Hussain… in Chemistry of Natural Compounds (2012)

  5. Article

    Antimalarial Compounds from the Root Bark of Garcinia polyantha Olv.

    Eight compounds were isolated from the roots of Garcinia polyantha, and identified. Two of them, the xanthone garciniaxanthone I (1), and the triterpene, named garcinane (2), are reported as new natural products....

    Alain Meli Lannang, Gabin Nselapi Louh, David Lontsi… in The Journal of Antibiotics (2008)

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  6. No Access

    Book

    Anthracycline Chemistry and Biology II

    Mode of Action, Clinical Aspects and New Drugs

    Karsten Krohn in Topics in Current Chemistry (2008)

  7. No Access

    Book

    Anthracycline Chemistry and Biology I

    Biological Occurence and Biosynthesis, Synthesis and Chemistry

    Karsten Krohn in Topics in Current Chemistry (2008)

  8. No Access

    Article

    Virulenzuntersuchungen an Mycocentrospora acerina (HARTIG) DEIGHTON, einem Blattfleckenerreger bei Stiefmütterchen

    Die Blattfleckenkrankheiten bei Stiefmütterchen werden durch mehrere Pflanzenpathogene verursacht, die große ökonomische Einbußen verursachen und nur schwer bekämpfbar sind. Über einen Zeitraum von drei Jahren...

    Bernd Gutter, Karsten Krohn, Volker Paul in Gesunde Pflanzen (2003)

  9. Article

    Benzamide riboside induces apoptosis independent of Cdc25A expression in human ovarian carcinoma N.1 cells

    One of the mechanisms of action of a new oncolytic agent, benzamide riboside (BR) is by inhibiting inosine 5′-monophosphate dehydrogenase (IMPDH) which catalyzes the formation of xanthine 5′-monophosphate from...

    Michael Grusch, Georg Rosenberger, Gerhard Fuhrmann… in Cell Death & Differentiation (1999)

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  10. No Access

    Chapter

    Angucyclines: Total syntheses, new structures, and biosynthetic studies of an emerging new class of antibiotics

    General and recent aspects of chemical syntheses on angucyclinones and selected related natural products are summarized here. In the first part of this review on angucyclines, the chemical reaction used as a k...

    Karsten Krohn, Jürgen Rohr in Bioorganic Chemistry Deoxysugars, Polyketi… (1997)

  11. No Access

    Article

    Biotechnological production of unnatural L-amino acids from D,L-5-monosubstituted hydantions. II. L-α- and L-β-naphthylalanine

    Resting cells ofArthrobacter sp. (DSM 3745) with the ability to form L-tryptophan from D,L-5-(3-indolylmethy)hydantoin were used for the bioconversion of D,L-5-α- and D,L-5-β-naphthylmethylhydantoin (D,L-5-α- and...

    Christoph Syldatk, Dirk Völkel, Ulrich Bilitewski, Karsten Krohn… in Biotechnology Letters (1992)

  12. No Access

    Article

    Biotechnological production of unnatural L-amino acids from D,L-5-monosubstituted hydantions. I. Derivatives of L-phenylalanine

    Resting cells of a mutant ofArthrobacter sp. (DSM 3747) were used for the bioconversion of D,L-5-benzylhydantoin and related compounds to the corresponding L-amino acids. After optimization of the reaction condit...

    Christoph Syldatk, Vera Lehmensiek, Gaby Ulrichs… in Biotechnology Letters (1992)

  13. No Access

    Article

    Übersichtsbeiträge

    Martin Kreutzer, Karsten Krohn… in Umweltwissenschaften und Schadstoff-Forschung (1990)