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Angucyclines: Total syntheses, new structures, and biosynthetic studies of an emerging new class of antibiotics

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Bioorganic Chemistry Deoxysugars, Polyketides and Related Classes: Synthesis, Biosynthesis, Enzymes

Part of the book series: Topics in Current Chemistry ((4143,volume 188))

Abstract

General and recent aspects of chemical syntheses on angucyclinones and selected related natural products are summarized here. In the first part of this review on angucyclines, the chemical reaction used as a key step for the construction of the angucyclinone frame is discussed. In the second part, new members of the angucycline group of antibiotics, their bioactivity and recent biosynthetic studies including modern aspects of molecular biology (genetics) are reviewed.

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  1. Fachbereich Chemie und Chemietechnik, Universität-GH Paderborn, Warburger Straße 100, 33098, Paderborn, Germany

    Karsten Krohn

  2. Institut für Organische Chemie, Universität Göttingen, Tammannstr. 2, 37077, Göttingen, Germany

    Jürgen Rohr

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Krohn, K., Rohr, J. (1997). Angucyclines: Total syntheses, new structures, and biosynthetic studies of an emerging new class of antibiotics. In: Rohr, J. (eds) Bioorganic Chemistry Deoxysugars, Polyketides and Related Classes: Synthesis, Biosynthesis, Enzymes. Topics in Current Chemistry, vol 188. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0119236

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