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Open AccessRole of Berberine in the Treatment of Methicillin-Resistant Staphylococcus aureus Infections
Berberine is an isoquinoline alkaloid widely used in the treatment of microbial infections. Recent studies have shown that berberine can enhance the inhibitory efficacy of antibiotics against clinical multi-dr...
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Open AccessCART treatment improves memory and synaptic structure in APP/PS1 mice
Major characteristics of Alzheimer’s disease (AD) include deposits of β-amyloid (Aβ) peptide in the brain, loss of synapses and cognitive dysfunction. Cocaine- and amphetamine-regulated transcript (CART) has r...
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Open AccessMalibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner
Activation of microglia plays a crucial role in immune and inflammatory processes after ischemic stroke. Microglia is reported with two opposing activated phenotypes, namely, classic phenotype (M1) and the alt...