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Chapter
Frequency of the Delta-F508 Mutation and Flanking Marker Haplotypes at the Cystic Fibrosis Locus from 167 Czech Families
This study was undertaken in order to compare the predominantly Slavic Czech Cystic Fibrosis (CF) population of Bohemia and Moravia (Czech Republic of Czechoslovakia) with other Caucasian populations in Europe...
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Article
Molekulargenetische Diagnostik: aktueller Stand — zukünftige Perspektiven
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Article
Description of a chromosome replication unit in individual prematurely condensed human S-phase chromosomes
Mammalian chromosome replication was studied by the aid of premature chromosome condensation (PCC). After induction of PCC the sites of DNA replication appear as “gaps” between condensed chromosomal regions. T...
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Chapter and Conference Paper
Frequency and Origin of Chromosome Abnormalities in Man
During the past 25 years human cytogenetics has changed from a highly specialized academic discipline restricted to only a few institutions to a rapidly expanding area of research and routine application invol...
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Article
Evolution of muntjac DNA
The extent of nuclear single-copy DNA divergence between Muntiacus reevesi and Muntiacus muntjak vaginalis (Cervidae), a species pair showing extreme karyotype differences but striking morphological similarity, i...
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Article
Arrangement of prematurely condensed chromosomes in cultured cells and lymphocytes of the Indian muntjac
Premature chromosome condensation (PCC) was induced in order to study the arrangement of muntjac chromosomes in the interphase nuclei of proliferating and resting cells with respect to their polarity and the s...
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Article
A simple staining technique to demonstrate chromosomal DNA replication
With the BrdU technique here described, Giemsa stained metaphases with either early or late, replicational patterns can be obtained within 1 day after cell harvesting, showing a better resolution than3H-thymidine...