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  1. Article

    Open Access

    IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV

    CD8+ T-cell functions are critical for preventing chronic viral infections by eliminating infected cells. For healthy immune responses, beneficial destruction of infected cells must be balanced against immunopath...

    M Grusdat, D R McIlwain, H C Xu, V I Pozdeev, J Knievel in Cell Death & Differentiation (2014)

  2. Article

    Phosphorylation of Atg5 by the Gadd45β–MEKK4-p38 pathway inhibits autophagy

    Autophagy is a lysosomal degradation pathway important for cellular homeostasis, mammalian development, cancer and immunity. Many molecular components of autophagy have been identified, but little is known abo...

    E Keil, R Höcker, M Schuster, F Essmann, N Ueffing in Cell Death & Differentiation (2013)