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    Chapter

    Defeating Randomness – Targeted Integration as a Boost for Biotechnology

    Genetic modification of mammalian cells is a prerequisite for the production of recombinant proteins, virus like particles, and viruses. For most applications long-term stability of such modifications is neede...

    L. Gama-Norton, P. Riemer, U. Sandhu, K. Nehlsen, R. Schucht in Cell Line Development (2009)