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  1. No Access

    Chapter

    2, 8-Dihydroxyadeninuria: Or When is a Uric Acid Stone not a Uric Acid Stone?

    Purine nucleotides important for normal cellular metabolism are derived endogenously from de novo synthesis and also from recycling of pre-formed purines via the so-called salvage pathway (Figure 1). The latter p...

    H. A. Simmonds, K. J. Van Acker, M. J. Dillon, T. M. Barratt, C. F. Potter… in Urolithiasis (1981)

  2. No Access

    Chapter

    Influence of Purine Content of Diet and Allopurinol on Uric Acid and Oxalate Excretion Levels

    A defect of the purine salvage enzyme adenine phosphoribosyl-transferase (APRT) results in lithiasis in some but not all homozygotes for the defect. The stones are frequently mistaken for uric acid1, but are real...

    H. A. Simmonds, K. J. Van Acker, C. F. Potter, D. R. Webster, G. P. Kasidas… in Urolithiasis (1981)

  3. No Access

    Chapter and Conference Paper

    ‘Uric Add’ Stones in Children: Problems of Diagnosis and Treatment in a New Defect— Adenine Phosphoribosyltransferase Deficiency

    Uric acid stones generally represent less than 10% of all renal stones in most adult populations. Stones per se are rare in childhood. In some instances a metabolic basis in purine metabolism may be identified...

    Dr H. A. Simmonds, J. S. Cameron, M. J. Dillon, T. M. Barratt… in Uric acid lithiasis (1981)

  4. No Access

    Chapter and Conference Paper

    Immunologically Mediated Tubulointerstitial Nephritis

    Various experimental studies have shown that tubulo-interstitial nephritis (TIN) may be mediated by auto-antibodies directed against components of the tubular basement membranes (TBM), but the mechanisms of th...

    M. Levy, M. F. Gagnadoux, M. Broyer, R. Habib, W. G. Couser… in Paediatric Nephrology (1984)

  5. No Access

    Article

    Recurrent haemolytic uraemic syndrome and acquired hypomorphic variant of the third component of complement

    In a girl with recurrent haemolytic uraemic syndrome (HUS), persistently low serum levels of C3 were found. Analysis of complement phenotype revealed a hypomorphic variant of C3 Fast in the patient (C3fS) and ...

    A. M. Roodhooft, R. H. McLean, E. Elst, K. J. Van Acker in Pediatric Nephrology (1990)

  6. No Access

    Article

    Protein restriction in chronic renal failure

    J. E. Kist-van Holthe tot Echten, J. Nauta, W. C. J. Hop… in Pediatric Nephrology (1993)

  7. No Access

    Article

    Acute interstitial nephritis and anterior uveitis

    K. J. Van Acker in Pediatric Nephrology (1994)

  8. No Access

    Article

    Anti-glomerular basement membrane glomerulopathy in a young child

    We report the youngest patient with anti-glomerular basement membrane disease described in the literature to date. Age-dependent expression of the target antigen in this auto-immune disease explains the low i...

    K. Boven, H. P. J. Miljoen, K. J. Van Hoeck, E. A. Van Marck… in Pediatric Nephrology (1996)