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Article
Open AccessHydrodynamics of the fast-start caridoid escape response in Antarctic krill, Euphausia superba
Krill are shrimp-like crustaceans with a high degree of mobility and variety of documented swimming behaviors. The caridoid escape response, a fast-start mechanism unique to crustaceans, occurs when the animal...
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Article
Metachronal swimming in Antarctic krill: gait kinematics and system design
Metachronal swimming, in which adjacent appendages stroke in sequence, is widespread among crustaceans inhabiting the transitional flow realm in which both viscosity and inertia effects are important. However,...
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Article
Cyclin-C-dependent cell-cycle entry is required for activation of non-homologous end joining DNA repair in postmitotic neurons
It is commonly believed that neurons remain in G0 phase of the cell cycle indefinitely. Cell-cycle re-entry, however, is known to contribute to neuronal apoptosis. Moreover, recent evidence demonstrates the expre...
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Article
Multipoint correlations of concentration fluctuations in a turbulent passive scalar field
This study experimentally analyzes a turbulent passive scalar field using two-point and three-point correlation functions of the concentration fluctuations. The scalar field was created by the iso-kinetic rele...
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Article
The effect of bed roughness on scalar fluctuations in turbulent boundary layers
The effect of bed roughness on an iso-kinetic chemical plume released into the logarithmic region of the bed boundary layer of an open channel flow is examined. The bed roughness is varied systematically to ge...
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Article
A Multidisciplinary Study of Spatial and Temporal Scales Containing Information in Turbulent Chemical Plume Tracking
This report describes the results of a multidisciplinary study of turbulent chemical plume tracking of blue crabs and autonomous agents. The study consists of a coordinated investigation of animal behavior, fl...
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Article
Velocity measurements of turbulence collapse in a linearly stratified jet
The behavior of a horizontal turbulent round jet␣in a linearly density-stratified fluid is studied and compared to the unstratified case using digital particle-tracking velocimetry (DPTV). Close to the nozzle...
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Article
Simultaneous DPTV/PLIF measurements of a turbulent jet
Simultaneous measurements of instantaneous velocity and concentration fields were performed using digital particle tracking velocimetry and planar laser- induced fluorescence for a turbulent jet at a Reynolds...
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Article
Jet pinch-off and drop formation in immiscible liquid–liquid systems
The behavior of glycerin–water jets flowing into immiscible ambients of Dow Corning 200 fluid was investigated using laser induced fluorescence (LIF). Undistorted images were obtained by matching the index of...
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Article
Use of intact erythrocytes in the diagnosis of inherited purine and pyrimidine disorders
This paper reports the detection of five inherited disorders of purine and one of pyrimidine metabolism using intact red blood cells (RBCs) and compares the findings with those from RBC lysate activity. Two di...
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Chapter
Purine Metabolism by Guinea-Pig Ileum
Adenosine and the 5′-adenine nucleotides inhibit cholinergic neurotransmission in guinea-pig ileum through actions at presynaptic P1-purinoceptors (Paton et al., 1985). However, it was not possible to show whethe...
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Chapter
Mechanism of Urate Production by Guinea-Pig Ileum
Previous studies have demonstrated considerable efflux of purine consisting mostly uric acid but with smaller quantities of xanthine, hypoxanthine, inosine and adenosine) from isolated guinea-pig ileal segment...
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Article
Failure of protein loading tests to identify heterozygosity for ornithine carbamoyltransferase deficiency
Protein loading tests for the diagnosis of heterozygous ornithine carbamoyltransferase deficiency were performed on two occasions on an asymptomatic woman whose daughter and two infant sons died of the disease...
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Article
Pregnancy in xanthinuria: Demonstration of fetal uric acid production?
This paper reports biochemical studies in a pregnant xanthinuric female (McKusick 27830) and compares the results with findings in three other xanthinurics studied by us, including a previously unreported fema...
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Chapter
New Perspectives in the Diagnosis and Treatment of Adenosine Deaminase (ADA) Deficiency
Severe combined immunodeficiency (SCID) due to adenosine deaminase deficiency (ADA) exhibits autosomal recessive inheritance, and may account for up to 20% of cases (1). Accumulation of intracellular toxic deo...
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Chapter
Gout Resistant to Allopurinol: Poor Compliance or Non-Response
Patients with chronic gouty arthritis unresponsive to allopurinol are generally dismissed as poor compliers. This paper presents studies in a middle-aged male with a 20-year history of gout in whom allopurinol...
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Chapter
Evidence of A New Syndrome Involving Hereditary Uric Acid Overproduction, Neurological Complications and Deafness
Hypoxanthiye-guanine phosphoribosyltransferase (HGPRT: EC 2.4.2.8) deficiency is an X-linked recessive disorder which may present in early infancy as the Lesch-Nyhan syndrome associated with gross purine overp...
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Chapter
Inosine Formation from Hypoxanthine by Intact Erythrocytes and Fibroblasts of an Immunodeficient Child with Purine Nucleoside Phosphorylase Deficiency
Detailed studies of purine metabolism have been carried out over an 18 month period in a neonate with severe T-cell immunodeficiency(Watson et al, this symposium). A complete deficiency of the enzyme purine nu...
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Chapter
Problems of Diagnosis in an Adolescent with Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency and Acute Renal Failure
In hypoxanthine-guanine phosphoribosyltransferase (E.C 2.4.2.8, HGPRT) deficiency1,2 the clinical manifestations usually parallel the amount of residual enzyme. Thus, patients with the full Lesch-Nyhan syndrome, ...
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Chapter
Nucleotide Levels and Metabolism of Adenosine and Deoxyadenosine in Intact Erythrocytes Deficient in Adenosine Deaminase
We previously reported severe ATP depletion in the erythrocytes of an adenosine deaminase (ADA: EC 3.5.4.4) deficient child and also found raised dAMP levels1 in addition to the raised dATP and dADP levels noted ...
