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Open AccessEvaluation of large airway specimens obtained by transbronchial lung cryobiopsy in diffuse parenchymal lung diseases
The difference in diagnostic yield between surgical lung biopsy and transbronchial lung cryobiopsy (TBLC) in diffuse parenchymal lung diseases (DPLD) has been reported to be due to differences in the rate of i...
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Article
Open AccessAutoimmune pulmonary alveolar proteinosis developed during immunosuppressive treatment in polymyositis with interstitial lung disease: a case report
Pulmonary alveolar proteinosis (PAP) is characterized by the accumulation of surfactant proteins within the alveolar spaces. Autoimmune PAP (APAP) caused by elevated levels of GM-CSF autoantibodies (GM-Ab) is ...
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Article
Thermody namic functions of 1,2-alkanediols in dilute aqueous solutions
The heat capacities of binary aqueous solutions of 1,2-ethanediol, 1,2-propanediol and 1,2-butanediol were measured at temperatures ranging from 283.15 to 338.15 K by differential scanning calorimetry. The par...
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Article
Sea urchin insulator protects lentiviral vector from silencing by maintaining active chromatin structure
Suppressed expression of transgenes in vivo is the major obstacle in the gene therapy. For the long-term expression, we utilized a chromatin insulator from sea urchin arylsulfatase (Ars) gene locus (Ars insulator...
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Article
An insulator element from the sea urchin Hemicentrotus pulcherrimus suppresses variation in transgene expression in cultured tobacco cells
Specialized DNA sequences known as insulators protect genes from both the positive and negative influences of nearby chromatin. Many insulators have been identified in various species; however, few function i...
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Article
CAAT sites are required for the activation of the H. pulcherrimus Ars gene by Otx
A product of sea urchin homologues of the Drosophila orthodenticle gene, HpOtxL has been implicated as a transcription activator of the aboral ectoderm-specific arylsulfatase (Ars) gene during early development o...
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Article
Identification and Determination of Low-Molecular Weight Organic Compounds in Contaminated Fog Water Using Proton Nuclear Magnetic Resonance Spectroscopy
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Article
Combination Antibacterial Therapy in Patients with Haematological Disorders
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Article
31P-NMR study on nucleotides and intracellular pH of hereditary spherocytes
As determined by31p-NMR spectroscopy, intracellarar pH of hereditary spherocytes was lower (pH 6.7–6.9) than that of normal red cells. The level of adenosine diphosphate in hereditary spherocytes was found to be ...
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Article
Unusual segmental flexibility in a region of tobacco mosaic virus coat protein
ASSEMBLY of tobacco mosaic virus (TMV) is known to occur by threading in the RNA on the inner side of the growing hollow rodlet of viral coat protein, and is thought to involve a pre-assembled double disk as a...
