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    Article

    p53 negatively regulates the expression of FAT10, a gene upregulated in various cancers

    FAT10 is a member of the ubiquitin-like modifier family of proteins and has been implicated to play important roles in antigen presentation, cytokine response, apoptosis and mitosis. We have recently demonstra...

    D W Zhang, K-T Jeang, C G L Lee in Oncogene (2006)

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    The N-terminus of rodent and human MAD1 confers species-specific stringency to spindle assembly checkpoint

    The spindle assembly checkpoint (SAC) guards against chromosomal mis-segregation and the emergence of aneuploidy. SAC in higher eukaryotes includes at least 10 proteins including MAD1-3, BUB1-3, and Msp1. A lo...

    K Haller, K V Kibler, T Kasai, Y-H Chi, J-M Peloponese, V S R K Yedavalli in Oncogene (2006)

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    Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy

    The human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus discovered to be causative of a human cancer, adult T-cell leukemia. The transforming entity of HTLV-1 has been attributed to the virall...

    M Matsuoka, K-T Jeang in Oncogene (2011)