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  1. Article

    Open Access

    Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model mice

    In the peripheral blood leukocytes (PBLs) from the carriers of the human T-lymphotropic virus type-1 (HTLV-1) or the patients with adult T-cell leukemia (ATL), nuclear factor kappaB (NF-κB)-mediated antiapopto...

    E Ikebe, A Kawaguchi, K Tezuka, S Taguchi, S Hirose, T Matsumoto… in Blood Cancer Journal (2013)

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    Article

    Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy

    The human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus discovered to be causative of a human cancer, adult T-cell leukemia. The transforming entity of HTLV-1 has been attributed to the virall...

    M Matsuoka, K-T Jeang in Oncogene (2011)

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    Article

    p53 negatively regulates the expression of FAT10, a gene upregulated in various cancers

    FAT10 is a member of the ubiquitin-like modifier family of proteins and has been implicated to play important roles in antigen presentation, cytokine response, apoptosis and mitosis. We have recently demonstra...

    D W Zhang, K-T Jeang, C G L Lee in Oncogene (2006)

  4. No Access

    Article

    The N-terminus of rodent and human MAD1 confers species-specific stringency to spindle assembly checkpoint

    The spindle assembly checkpoint (SAC) guards against chromosomal mis-segregation and the emergence of aneuploidy. SAC in higher eukaryotes includes at least 10 proteins including MAD1-3, BUB1-3, and Msp1. A lo...

    K Haller, K V Kibler, T Kasai, Y-H Chi, J-M Peloponese, V S R K Yedavalli… in Oncogene (2006)

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    Chapter

    Comparison of Regulatory Features Among Primate Lentiviruses

    It has been more than a decade since the description of primate lentiviruses as the etiological agents for immunodeficiencies (Barre—Sinoussi et al. 1983; Gallo et al. 1984; Levy et al. 1984; Clavel et al. 1986)....

    K. T. Jeang, A. Gatignol in Simian Immunodeficiency Virus (1994)