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  1. No Access

    Article

    Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin

    The human immunodeficiency virus type 1 (HIV-1) viral protein R (vpr) gene is an evolutionarily conserved gene among the primate lentiviruses. Several functions are attributed to Vpr including the ability to caus...

    K Siddiqui, L Del Valle, N Morellet, J Cui, M Ghafouri, R Mukerjee, K Urbanska… in Oncogene (2008)

  2. No Access

    Article

    Inhibition of IGF-I receptor in anchorage-independence attenuates GSK-3β constitutive phosphorylation and compromises growth and survival of medulloblastoma cell lines

    We have previously reported that insulin-like growth factor-I (IGF-I) supports growth and survival of mouse and human medulloblastoma cell lines, and that IGF-I receptor (IGF-IR) is constitutively phosphorylat...

    K Urbanska, J Trojanek, L Del Valle, M B Eldeen, F Hofmann, C Garcia-Echeverria… in Oncogene (2007)

  3. No Access

    Article

    Role of the interaction between large T antigen and Rb family members in the oncogenicity of JC virus

    Human polyomaviruses (JC virus, BK virus and simian virus 40) are causative agents of some human diseases and, interestingly, are involved in processes of cell transformation and oncogenesis. These viruses nee...

    V Caracciolo, K Reiss, K Khalili, G De Falco, A Giordano in Oncogene (2006)

  4. No Access

    Article

    Efficient in vitro and in vivo gene regulation of a retrovirally delivered pro-apoptotic factor under the control of the Drosophila HSP70 promoter

    We have developed a self-inactivating retroviral vector system with an internal, inducible Drosophila HSP70 promoter. This vector system delivers the desired transgene into cells rapidly and efficiently. It ge...

    G Romano, K Reiss, X Tu, F Peruzzi, B Belletti, J Y Wang, T Zanocco-Marani… in Gene Therapy (2001)