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Article
Open AccessShort-Term Impact of Seizures and Mitigation Opportunities
The burden of epilepsy is complex and consists of elements directly related to acute seizures as well as those associated with living with a chronic neurologic disorder. The purpose of this systematic review w...
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Article
Publisher Correction to: Morphological Features of Language Regions in Individuals with Tuberous Sclerosis Complex
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Article
Morphological Features of Language Regions in Individuals with Tuberous Sclerosis Complex
A significant number of individuals with tuberous sclerosis complex (TSC) exhibit language difficulties. Here, we examined the language-related brain morphometry in 59 participants (7 participants with TSC and...
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Article
Open AccessA structural brain network of genetic vulnerability to psychiatric illness
Psychiatry is undergoing a paradigm shift from the acceptance of distinct diagnoses to a representation of psychiatric illness that crosses diagnostic boundaries. How this transition is supported by a shared n...
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Article
EEG Spectral Features in Sleep of Autism Spectrum Disorders in Children with Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is a multisystem disorder with increased prevalence of autism spectrum disorders (ASDs). This project aimed to characterize the autism phenotype of TSC and identify biomarkers ...
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Article
Update on Drug Management of Refractory Epilepsy in Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is a genetic neurocutaneous disorder with epilepsy as a common and early presenting symptom. The neurological phenotype, however, is variable and unpredictable. Early and refra...
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Article
Open AccessEarly white matter development is abnormal in tuberous sclerosis complex patients who develop autism spectrum disorder
Autism spectrum disorder (ASD) is prevalent in tuberous sclerosis complex (TSC), occurring in approximately 50% of patients, and is hypothesized to be caused by disruption of neural circuits early in life. Tub...
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Article
Tuberous Sclerosis: A New Frontier in Targeted Treatment of Autism
Tuberous sclerosis complex (TSC) is a genetic disorder with a high prevalence of autism spectrum disorder (ASD). Tremendous progress in understanding the pathogenesis of TSC has been made in recent years, alon...
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Chapter and Conference Paper
A Fully Bayesian Inference Framework for Population Studies of the Brain Microstructure
Models of the diffusion-weighted signal are of strong interest for population studies of the brain microstructure. These studies are typically conducted by extracting a scalar property from the model and subje...
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Article
Electrode localization for planning surgical resection of the epileptogenic zone in pediatric epilepsy
In planning for a potentially curative resection of the epileptogenic zone in patients with pediatric epilepsy, invasive monitoring with intracranial EEG is often used to localize the seizure onset zone and...
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Chapter and Conference Paper
Four Neuroimaging Questions that P-Values Cannot Answer (and Bayesian Analysis Can)
Null Hypothesis Significance Testing (NHST) is used pervasively in neuroimaging studies, despite its known limitations. Recent critiques to these tests have mostly focused on technical issues with multiple com...
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Article
Open AccessBrain functional networks in syndromic and non-syndromic autism: a graph theoretical study of EEG connectivity
Graph theory has been recently introduced to characterize complex brain networks, making it highly suitable to investigate altered connectivity in neurologic disorders. A current model proposes autism spectrum...
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Article
Spinal cord involvement in a child with raccoon roundworm (Baylisascaris procyonis) meningoencephalitis
A 14-month-old previously healthy boy developed progressively worsening neurological symptoms secondary to eosinophilic meningoencephalitis with myelitis caused by raccoon roundworm (Baylisascaris procyonis) infe...