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Article
Signature and function of plasma exosome-derived circular RNAs in patients with hypertensive intracerebral hemorrhage
Intracerebral hemorrhage (ICH) is one of the major causes of death and disability, and hypertensive ICH (HICH) is the most common type of ICH. Currently, the outcomes of HICH patients remain poor after treatme...
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Article
The Asymmetric Reduction of Acetophenone and Its Derivatives to (S)-Aromatic Secondary Alcohols by Rhodotorula mucilaginosa CCTCC M2014255 Resting Cells
Enantiomerically enriched aromatic secondary alcohols and its derivatives are important chiral intermediates utilized widely in pharmacy, chemical, hormone, spices and chiral auxiliary materials. Thus, the key...
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Article
Open AccessThe mechanism of apoliprotein A1 down-regulated by Hepatitis B virus
Hepatitis B virus (HBV) infection correlated with the development of cirrhosis, liver failure and hepatocellular carcinoma (HCC), poses a huge health burden on the global community. However, the pathogenesis o...
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Article
Open AccessA cross-talk between Hepatitis B virus and host mRNAs confers viral adaptation to liver
Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide. The replication of HBV which genome is only 3.2 kb long relies heavily on host factors. Previous studies demonstrated tha...
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Article
Open AccessCompetitive virus and host RNAs: the interplay of a hidden virus and host interaction
During virus infection, viral RNAs and mRNAs function as blueprints for viral protein synthesis and possibly as pathogen-associated molecular patterns (PAMPs) in innate immunity. Here, considering recent resea...
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Article
MiR-122 in hepatic function and liver diseases
As the most abundant liver-specific microRNA, microRNA-122 (miR-122) is involved in various physiological processes in hepatic function as well as in liver pathology. There is now compelling evidence that miR-...
