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  1. Article

    Author Correction: MYC phase separation selectively modulates the transcriptome

    Junjiao Yang, Chan-I Chung, Jessica Koach… in Nature Structural & Molecular Biology (2024)

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    Article

    MYC phase separation selectively modulates the transcriptome

    Dysregulation and enhanced expression of MYC transcription factors (TFs) including MYC and MYCN contribute to the majority of human cancers. For example, MYCN is amplified up to several hundredfold in high-risk n...

    Junjiao Yang, Chan-I Chung, Jessica Koach… in Nature Structural & Molecular Biology (2024)

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    Article

    Synthesis and ultraviolet/aggregation-induced emission investigation of novel tetraphenylvinyl hydrazone derivatives: efficient multimodal chemosensors for fluoride ion

    Herein, three novel tetraphenylethylene hydrazone chemosensors TC12, SC16, and TC16 are prepared for the selective detection of F−. Two NH and one C=N units are incorporated into the sensors for better colorimetr...

    Wenting Yin, Linqi Shi, Mengjiao Liang… in Frontiers of Chemical Science and Engineer… (2023)

  4. Article

    Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2

    The coronavirus SARS-CoV-2 causes the severe disease COVID-19. SARS-CoV-2 infection is initiated by interaction of the viral spike protein and host receptor angiotensin-converting enzyme 2 (ACE2). We report an...

    Junjiao Yang, Yinghong **ao, Peter V. Lidsky, Chien-Ting Wu… in Nature Microbiology (2023)

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    Article

    Designed peptides that assemble into cross-α amyloid-like structures

    Amyloids adopt ‘cross-β’ structures composed of long, twisted fibrils with β-strands running perpendicular to the fibril axis. Recently, a toxic peptide was proposed to form amyloid-like cross-α structures in ...

    Shao-Qing Zhang, Hai Huang, Junjiao Yang, Huong T. Kratochvil… in Nature Chemical Biology (2018)

  6. Article

    Open Access

    Glucosyltransferase Activity of Clostridium difficile Toxin B Triggers Autophagy-mediated Cell Growth Arrest

    Autophagy is a bulk cell-degradation process that occurs through the lysosomal machinery, and many reports have shown that it participates in microbial pathogenicity. However, the role of autophagy in Clostridium...

    Ruina He, **gyu Peng, Pengfei Yuan, Junjiao Yang, **aoji Wu… in Scientific Reports (2017)

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    Protocol

    Assembly of Customized TAL Effectors Through Advanced ULtiMATE System

    Transcription activator-like effectors (TALEs) have been widely applied in gene targeting. Here we describe an advanced ULtiMATE (USER-based Ligation-Mediated Assembly of TAL Effector) system that utilizes USER f...

    Junjiao Yang, Shengjie Guo, Pengfei Yuan, Wensheng Wei in TALENs (2016)

  8. Article

    Open Access

    Complete decoding of TAL effectors for DNA recognition

    Junjiao Yang, Yuan Zhang, Pengfei Yuan, Yuexin Zhou, Changzu Cai… in Cell Research (2014)

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    Article

    Synthesis, characterization, crystal structure and antitumor activities of a novel demethylcantharidato bridged copper(II) phenanthroline complex

    A new polymeric demethylcantharidato (DCA) bridged copper(II) phenanthroline (phen) complex ([Cu(DCA)(phen)] n ·nH2O) has been synthesized and characterized by elemental analysis...

    FuLing Yin, **g**g Zhu, Jian Hao, **gRong Cui, JunJiao Yang in Science China Chemistry (2013)