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Article
Open AccessRelationship between mortality and use of sodium bicarbonate at the time of dialysis initiation: a prospective observational study
Patients with chronic kidney disease often experience metabolic acidosis. Whether oral sodium bicarbonate can reduce mortality in patients with metabolic acidosis has been debated for years. Hence, this study ...
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Article
Thrombotic microangiopathy on kidney biopsy in a patient with TAFRO syndrome
TAFRO syndrome represents a characteristic constellation of symptoms comprising Thrombocytopenia, Anasarca, myeloFibrosis, Renal dysfunction, and Organomegaly, and is considered to be a clinicopathologic varia...
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Article
Recurrent infectious subcapsular renal hematoma accompanied by microaneurysm
An 80-year-old woman was admitted to the hospital complaining of loss of appetite. 10 days earlier, her oral intake gradually decreased with no other specific symptoms, such as abdominal pain, nausea, vomiting...
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Article
Overwork accelerates thrombotic reaction: implications for the pathogenesis of Karoshi
Work-related stressors are potential causes of cardiovascular diseases (CVDs) and stroke; however, the pathophysiological mechanisms by which occupational stress induces and exacerbates CVDs remain unclear. Th...
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Article
Open AccessGlobal Thrombosis Test – a possible monitoring system for the effects and safety of dabigatran
Dabigatran is an alternative to warfarin (WF) for the thromboprophylaxis of stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran over WF is that monitoring is not requir...
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Article
Open AccessEnhanced pre-operative thrombolytic status is associated with the incidence of deep venous thrombosis in patients undergoing total knee arthroplasty
Deep venous thrombosis (DVT), which is often associated with pulmonary embolism (PE), is a serious complication after total knee arthroplasty (TKA). In the present study, we examined the overall thrombotic and...
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Article
Attenuation of spontaneous thrombolytic activity measured by the global thrombosis test in male habitual smokers
Smoking is known as one of the major risk factors for atherothrombotic cardiovascular diseases. We investigated the susceptibility to thrombosis in habitual smokers by using the global thrombosis test (GTT), b...
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Article
Open AccessDistribution of hydrogen sulfide (H2S)-producing enzymes and the roles of the H2S donor sodium hydrosulfide in diabetic nephropathy
Hydrogen sulfide (H2S) has recently been found to play beneficial roles in ameliorating several diseases, including hypertension, atherosclerosis and cardiac/renal ischemia–reperfusion injuries. Cystathionine β-s...
