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Open AccessA study on the fabrication of metal microneedle array electrodes for ECG detection based on low melting point Bi–In–Sn alloys
This study describes the fabrication and characteristics of microneedle array electrodes (MAEs) using Bismuth–Indium–Tin (Bi–In–Sn) alloys. The MAEs consist of 57 pyramid-shaped needles measuring 340 μm wide a...
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Open AccessFlash-Induced High-Throughput Porous Graphene via Synergistic Photo-Effects for Electromagnetic Interference Shielding
Flash-induced porous graphene (FPG) was synthesized via a broad-spectrum flash lamp that induced synergistic photo-effects between ultraviolet and visible-near-infrared wav...
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Open AccessSubaqueous 3D stem cell spheroid levitation culture using anti-gravity bioreactor based on sound wave superposition
Recently, various studies have revealed that 3D cell spheroids have several advantages over 2D cells in stem cell culture. However, conventional 3D spheroid culture methods have some disadvantages and limitati...
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Open AccessAuthor Correction: Development of the H3N2 influenza microneedle vaccine for cross-protection against antigenic variants
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Open AccessSingle-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia
Valvular inflammation triggered by hyperlipidemia has been considered as an important initial process of aortic valve disease; however, cellular and molecular evidence remains unclear. Here, we assess the rela...
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Open AccessDevelopment of the H3N2 influenza microneedle vaccine for cross-protection against antigenic variants
Due to the continuously mutating nature of the H3N2 virus, two aspects were considered when preparing the H3N2 microneedle vaccines: (1) rapid preparation and (2) cross-protection against multiple antigenic va...
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Microneedle technologies
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Open AccessLaser-induced graphitization of polydopamine leads to enhanced mechanical performance while preserving multifunctionality
Polydopamine (PDA) is a simple and versatile conformal coating material that has been proposed for a variety of uses; however in practice its performance is often hindered by poor mechanical properties and hig...
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Open AccessDisease-specific factors associated with cardiovascular events in patients with Takayasu arteritis
To identify disease-specific factors associated with cardiovascular events in patients with Takayasu arteritis (TAK).
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Open AccessNon-histologic factors discriminating proliferative lupus nephritis from membranous lupus nephritis
To investigate non-histologic factors that can discriminate proliferative lupus nephritis (LN) from membranous LN in patients with systemic lupus erythematosus with renal manifestations.
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Open AccessUtility of the Z-score of log-transformed A Body Shape Index (LBSIZ) in the assessment for sarcopenic obesity and cardiovascular disease risk in the United States
Body mass index (BMI) has limited accuracy for predicting cardiovascular diseases (CVD) and is not capable of identifying sarcopenic obesity, the combination of sarcopenia (an age-associated decline in muscle ...
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Open AccessEffectiveness of Z-score of log-transformed A Body Shape Index (LBSIZ) in predicting cardiovascular disease in Korea: the Korean Genome and Epidemiology Study
Body mass index (BMI) and waist circumference (WC) have limitations in stratifying cardio-metabolic risks. Another obesity measure, A Body Shape Index (ABSI), has been introduced but its applicability remains ...
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Open AccessTat-HSP22 inhibits oxidative stress-induced hippocampal neuronal cell death by regulation of the mitochondrial pathway
Oxidative stress plays an important role in the progression of various neuronal diseases including ischemia. Heat shock protein 22 (HSP22) is known to protect cells against oxidative stress. However, the prote...
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Open AccessTat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation
Oxidative stress is highly involved in the development of diabetes mellitus by destruction of pancreatic β-cells. DJ-1 is an antioxidant protein and DJ-1 expression levels are known to be reduced in diabetes m...
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Open AccessUrinary adiponectin and albuminuria in non-diabetic hypertensive patients: an analysis of the ESPECIAL trial
Although adiponectin levels have been reported to be correlated with albuminuria, this issue remains unresolved in non-diabetic hypertensive subjects, particularly when urinary adiponectin is considered.
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Open AccessDevelopment of selective blockers for Ca2+-activated Cl- channel using Xenopus laevis oocytes with an improved drug screening strategy
Ca2+-activated Cl- channels (CaCCs) participate in many important physiological processes. However, the lack of effective and selective blockers has hindered the study of these channels, mostly due to the lack of...