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Pharmaceutical and Immunological Evaluation of Cholera Toxin A1 Subunit as an Adjuvant of Hepatitis B Vaccine Microneedles

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  1. Article

    Open Access

    A study on the fabrication of metal microneedle array electrodes for ECG detection based on low melting point Bi–In–Sn alloys

    This study describes the fabrication and characteristics of microneedle array electrodes (MAEs) using Bismuth–Indium–Tin (Bi–In–Sn) alloys. The MAEs consist of 57 pyramid-shaped needles measuring 340 μm wide a...

    Hyunjong Gwak, Sungbo Cho, Yoon-Jae Song, Jung-Hwan Park, Soonmin Seo in Scientific Reports (2023)

  2. Article

    Open Access

    Flash-Induced High-Throughput Porous Graphene via Synergistic Photo-Effects for Electromagnetic Interference Shielding

  3. Flash-induced porous graphene (FPG) was synthesized via a broad-spectrum flash lamp that induced synergistic photo-effects between ultraviolet and visible-near-infrared wav...

  4. ** Soo Lee, Jeong-Wook Kim, Jae Hee Lee, Yong Koo Son, Young Bin Kim in Nano-Micro Letters (2023)

  5. Article

    Open Access

    Subaqueous 3D stem cell spheroid levitation culture using anti-gravity bioreactor based on sound wave superposition

    Recently, various studies have revealed that 3D cell spheroids have several advantages over 2D cells in stem cell culture. However, conventional 3D spheroid culture methods have some disadvantages and limitati...

    Jung Hwan Park, Ju-Ro Lee, Sungkwon Park, Yu-** Kim in Biomaterials Research (2023)

  6. Article

    Open Access

    Author Correction: Development of the H3N2 influenza microneedle vaccine for cross-protection against antigenic variants

    Yura Shin, Jeonghun Kim, Jong Hyeon Seok, Heedo Park, Hye-Ran Cha in Scientific Reports (2022)

  7. Article

    Open Access

    Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia

    Valvular inflammation triggered by hyperlipidemia has been considered as an important initial process of aortic valve disease; however, cellular and molecular evidence remains unclear. Here, we assess the rela...

    Seung Hyun Lee, Nayoung Kim, Minkyu Kim, Sang-Ho Woo, Inhee Han in Nature Communications (2022)

  8. Article

    Open Access

    Development of the H3N2 influenza microneedle vaccine for cross-protection against antigenic variants

    Due to the continuously mutating nature of the H3N2 virus, two aspects were considered when preparing the H3N2 microneedle vaccines: (1) rapid preparation and (2) cross-protection against multiple antigenic va...

    Yura Shin, Jeonghun Kim, Jong Hyeon Seok, Heedo Park, Hye-Ran Cha in Scientific Reports (2022)

  9. Article

    Microneedle technologies

    Seong-O Choi, Jung-Hwan Park in Drug Delivery and Translational Research (2022)

  10. Article

    Open Access

    Laser-induced graphitization of polydopamine leads to enhanced mechanical performance while preserving multifunctionality

    Polydopamine (PDA) is a simple and versatile conformal coating material that has been proposed for a variety of uses; however in practice its performance is often hindered by poor mechanical properties and hig...

    Kyueui Lee, Minok Park, Katerina G. Malollari, Jisoo Shin in Nature Communications (2020)

  11. Article

    Open Access

    Disease-specific factors associated with cardiovascular events in patients with Takayasu arteritis

    To identify disease-specific factors associated with cardiovascular events in patients with Takayasu arteritis (TAK).

    Oh Chan Kwon, Jung Hwan Park, Yong-Beom Park, Min-Chan Park in Arthritis Research & Therapy (2020)

  12. Article

    Open Access

    Non-histologic factors discriminating proliferative lupus nephritis from membranous lupus nephritis

    To investigate non-histologic factors that can discriminate proliferative lupus nephritis (LN) from membranous LN in patients with systemic lupus erythematosus with renal manifestations.

    Oh Chan Kwon, Jung Hwan Park, Hyeong-Cheon Park in Arthritis Research & Therapy (2020)

  13. Article

    Open Access

    Utility of the Z-score of log-transformed A Body Shape Index (LBSIZ) in the assessment for sarcopenic obesity and cardiovascular disease risk in the United States

    Body mass index (BMI) has limited accuracy for predicting cardiovascular diseases (CVD) and is not capable of identifying sarcopenic obesity, the combination of sarcopenia (an age-associated decline in muscle ...

    Wankyo Chung, Jung Hwan Park, Hye Soo Chung, Jae Myung Yu in Scientific Reports (2019)

  14. Article

    Open Access

    Effectiveness of Z-score of log-transformed A Body Shape Index (LBSIZ) in predicting cardiovascular disease in Korea: the Korean Genome and Epidemiology Study

    Body mass index (BMI) and waist circumference (WC) have limitations in stratifying cardio-metabolic risks. Another obesity measure, A Body Shape Index (ABSI), has been introduced but its applicability remains ...

    Shinje Moon, Jung Hwan Park, Ohk-Hyun Ryu, Wankyo Chung in Scientific Reports (2018)

  15. Article

    Open Access

    Tat-HSP22 inhibits oxidative stress-induced hippocampal neuronal cell death by regulation of the mitochondrial pathway

    Oxidative stress plays an important role in the progression of various neuronal diseases including ischemia. Heat shock protein 22 (HSP22) is known to protect cells against oxidative stress. However, the prote...

    Hyo Sang Jo, Dae Won Kim, Min Jea Shin, Su Bin Cho, Jung Hwan Park in Molecular Brain (2017)

  16. Article

    Open Access

    Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation

    Oxidative stress is highly involved in the development of diabetes mellitus by destruction of pancreatic β-cells. DJ-1 is an antioxidant protein and DJ-1 expression levels are known to be reduced in diabetes m...

    Hyo Sang Jo, Hyun Ju Cha, Sang ** Kim, Hyeon Ji Yeo in Medicinal Chemistry Research (2016)

  17. Article

    Open Access

    Urinary adiponectin and albuminuria in non-diabetic hypertensive patients: an analysis of the ESPECIAL trial

    Although adiponectin levels have been reported to be correlated with albuminuria, this issue remains unresolved in non-diabetic hypertensive subjects, particularly when urinary adiponectin is considered.

    Seung Seok Han, Eun** Bae, Shin Young Ahn, Sejoong Kim, Jung Hwan Park in BMC Nephrology (2015)

  18. Article

    Open Access

    Development of selective blockers for Ca2+-activated Cl- channel using Xenopus laevis oocytes with an improved drug screening strategy

    Ca2+-activated Cl- channels (CaCCs) participate in many important physiological processes. However, the lack of effective and selective blockers has hindered the study of these channels, mostly due to the lack of...

    Soo-** Oh, Jung Hwan Park, Sungyu Han, Jae Kyun Lee, Eun Joo Roh in Molecular Brain (2008)