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  1. Article

    Open Access

    Development of selective blockers for Ca2+-activated Cl- channel using Xenopus laevis oocytes with an improved drug screening strategy

    Ca2+-activated Cl- channels (CaCCs) participate in many important physiological processes. However, the lack of effective and selective blockers has hindered the study of these channels, mostly due to the lack of...

    Soo-** Oh, Jung Hwan Park, Sungyu Han, Jae Kyun Lee, Eun Joo Roh… in Molecular Brain (2008)

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  2. No Access

    Article

    One step beyond lethal equivalents: characterization of deleterious loci in the rapid cycling Brassica rapa L. base population

    The total number of lethal equivalents as defined by Morton, Crow and Muller (1956) is a function of three parameters: M, the number of loci at which deleterious mutations can occur, q, the frequency of the de...

    Martin Lascoux, Jae Kyun Lee in Genetica (1998)

  3. No Access

    Chapter and Conference Paper

    Assessment of Deleterious Gene Models Using Predictive p-values

    Using both hierarchical modeling and Bayesian computing techniques, Lee, Newton, Nordheim and Kang (1994) proposed a complex statistical model for studying the characteristics of deleterious genes in plant spe...

    Jae Kyun Lee in Case Studies in Bayesian Statistics (1997)

  4. Article

    Number of lethal equivalents in human populations: how good are the previous estimates?

    Lee et al. (1996) recently developed a method for interval estimation of the number of lethal equivalents by using a hierarchical structure of likelihood functions. This hierarchical model consists of two multino...

    Jae Kyun Lee, Martin Lascoux, Erik V Nordheim in Heredity (1996)

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