17 Result(s)
within
Julian L. Ambrus Jr.
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Article
Carnitine Palmitoyl Transferase Deficiency in a University Immunology Practice
This report describes the clinical manifestations of 35 patients sent to a University Immunology clinic with a diagnosis of fatigue and exercise intolerance who were identified to have low carnitine palmitoyl ...
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Article
Open AccessThe Potential Role for Early Biomarker Testing as Part of a Modern, Multidisciplinary Approach to Sjögren’s Syndrome Diagnosis
Sjögren’s syndrome (SS) is a chronic and progressive multisystem autoimmune disease typically managed by rheumatologists. Diagnostic delays are common, due in large part to the non-specific and variable nature...
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Article
Open AccessAnalysis of novel Sjogren’s syndrome autoantibodies in patients with dry eyes
Dry eye is a common problem in Ophthalmology and may occur for many reasons including Sjogren’s syndrome (SS). Recent studies have identified autoantibodies, anti-salivary gland protein 1 (SP1), anti-carbonic ...
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Chapter
Therapeutic Use of Biologic Agents in Systemic Vasculitides
Treatment of aggressive small, medium and large vessel vasculitides has relied on various chemotherapeutic agents, such as cyclophosphamide and methotrexate, that are generally effective but carry various risk...
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Article
Open AccessGastrointestinal disease in Sjogren’s syndrome: related to food hypersensitivities
Patients with Sjogren’s syndrome (SS) frequently have irritable bowel like symptoms (IBS). Some have celiac sprue. The current studies were designed to examine the presence of food hypersensitivities in a popu...
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Open AccessInvestigation of novel autoantibodies in Sjogren’s syndrome utilizing Sera from the Sjogren’s international collaborative clinical alliance cohort
Sjogren’s syndrome (SS) is a chronic autoimmune disease mainly affecting salivary and lacrimal glands. Current diagnostic criteria for SS utilize anti-Ro and anti-La as serological markers. Animal models for S...
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Reversible cerebral vasoconstriction syndrome (RCVS) in antiphospholipid antibody syndrome (APLA): the role of centrally acting vasodilators. Case series and review of literature
Reversible cerebral vasoconstriction syndrome (RCVS) is Raynaud's phenomenon of the brain. Changes in neurological function are dependent upon which areas of the brain are deprived of normal blood flow. Antiph...
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Article
Open AccessAnti-salivary gland protein 1 antibodies in two patients with Sjogren’s syndrome: two case reports
Current diagnostic criteria for Sjogren’s syndrome developed by the American College of Rheumatology include the presence of antinuclear antibodies, rheumatoid factor, anti-Ro or anti-La autoantibodies. The pu...
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Article
Open AccessTemporal histological changes in lacrimal and major salivary glands in mouse models of Sjogren’s syndrome
Evidence in imaging studies suggests that there may be differences in glandular involvement in Sjogren’s syndrome (SS) depending on the stage of the disease. No detailed histological studies are available to s...
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Article
Open AccessMitochondrial myopathy presenting as fibromyalgia: a case report
To the best of our knowledge, we describe for the first time the case of a woman who met the diagnostic criteria for fibromyalgia, did not respond to therapy for that disorder, and was subsequently diagnosed b...
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Article
Open AccessMetabolic myopathy presenting with polyarteritis nodosa: a case report
To the best of our knowledge, we describe for the first time a patient in whom an unusual metabolic myopathy was identified after failure to respond to curative therapy for a systemic vasculitis, polyarteritis...
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Article
Open AccessHuman Immunodeficiency Virus-Type 1 LTR DNA contains an intrinsic gene producing antisense RNA and protein products
While viruses have long been shown to capitalize on their limited genomic size by utilizing both strands of DNA or complementary DNA/RNA intermediates to code for viral proteins, it has been assumed that human...
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Article
Evaluation of Chronic Urticaria in Patients with Hashimoto Thyroiditis
The coincidence of Hashimoto thyroiditis (HT) and chronic idiopathic urticaria (CIU) is a commonly observed phenomenon in western New York. Previous literature suggested that there may be a direct relationship...
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Chapter
Current Studies Examining Regulation of the Human B Cell Cycle
The study of human B cell physiology involves the evaluation of a wide array of functions performed by B lymphocytes including antigen presentation (1), maintenance of memory for antigen (2), lymphokine secret...
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Chapter
The Activation, Proliferation, and Differentiation of Human B Lymphocytes
Efforts to evaluate normal human B cell physiology have resulted in the development of a model in which a resting B cell must progress through stages of activation, proliferation, and differentiation before be...
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Chapter
Human B-Cell Growth and Differentiation Factors Secreted by T-Cell Hybridomas
Application of the technique of cell hybridization (Köhler and Milstein, 1975) to human and murine T lymphocytes has been an area of recent intense interest and investigation. T-cell hybridomas have been devel...
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Chapter
The Human B Cell Cycle: Activation, Proliferation, and Differentiation
The full expression of a competent immune response, either cell mediated or humoral, requires the precise cooperation of a number of cell types which communicate either by cell-to-cell contact or by soluble im...
